Lymphatic Vessel Endothelial Hyaluronic Acid Receptor 1 Recombinant Protein | mLYVE-1 Sf9 recombinant protein
Recombinant Mouse Lymphatic Vessel Endothelial Hyaluronic Acid Receptor 1, Sf9
Gene Names
Lyve1; Xlkd1; Lyve-1; Crsbp-1; 1200012G08Rik
Purity
Greater than 95.0% as determined by: (a)Analysis by RP-HPLC. (b)Analysis by SDS-PAGE.
Synonyms
Lymphatic Vessel Endothelial Hyaluronic Acid Receptor 1; Recombinant Mouse Lymphatic Vessel Endothelial Hyaluronic Acid Receptor 1; Sf9; LYVE1 Mouse Sf9; Lymphatic Vessel Endothelial Hyaluronic Acid Receptor 1 Mouse Recombinant; Lymphatic vessel endothelial hyaluronic acid receptor 1 precursor; LYVE-1; Cell surface retention sequence-binding protein 1; CRSBP-1; Hyaluronic acid receptor; Extracellular link domain-containing protein; mLYVE-1 Sf9 recombinant protein
Host
Insect Cells
Purity/Purification
Greater than 95.0% as determined by: (a)Analysis by RP-HPLC. (b)Analysis by SDS-PAGE.
Form/Format
LYVE1 was lyophilized from a concentrated (1 mg/ml) sterile solution containing no additives.
Sterile Filtered White lyophilized (freeze-dried) powder.
Sterile Filtered White lyophilized (freeze-dried) powder.
Sequence Length
318
Solubility
It is recommended to reconstitute the lyophilized LYVE1 in sterile water not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Preparation and Storage
Lyophilized sLYVE-1 although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution sLYVE-1 should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
Related Product Information for mLYVE-1 Sf9 recombinant protein
Description: Soluble LYVE1 Mouse Recombinant fused to a C-terminal His-tag (6xHis) produced in baculovirus is a monomeric, glycosylated, polypeptide containing 228 amino acids (Met-1 to Gly 228) and having a molecular mass of 25 kDa but as a result of glycosilation the Mw is 40 kDa. The LYVE-1 is purified by proprietary chromatographic techniques.
Introduction: LYVE-1 has been identified as a major receptor for HA (extracellular matrix glycosaminoglycan hyaluronan) on the lymph vessel wall. The deduced amino acid sequence of LYVE-1 predicts a 322-residue type I integral membrane polypeptide 41% similar to the CD44 HA receptor with a 212-residue extracellular domain containing a single Link module the prototypic HA binding domain of the Link protein superfamily. Like CD44, the LYVE-1 molecule binds both soluble and immobilized HA. However, unlike CD44, the LYVE-1 molecule colocalizes with HA on the luminal face of the lymph vessel wall and is completely absent from blood vessels. Hence, LYVE-1 is the first lymph-specific HA receptor to be characterized and is a uniquely powerful marker for lymph vessels themselves.
Introduction: LYVE-1 has been identified as a major receptor for HA (extracellular matrix glycosaminoglycan hyaluronan) on the lymph vessel wall. The deduced amino acid sequence of LYVE-1 predicts a 322-residue type I integral membrane polypeptide 41% similar to the CD44 HA receptor with a 212-residue extracellular domain containing a single Link module the prototypic HA binding domain of the Link protein superfamily. Like CD44, the LYVE-1 molecule binds both soluble and immobilized HA. However, unlike CD44, the LYVE-1 molecule colocalizes with HA on the luminal face of the lymph vessel wall and is completely absent from blood vessels. Hence, LYVE-1 is the first lymph-specific HA receptor to be characterized and is a uniquely powerful marker for lymph vessels themselves.
Product Categories/Family for mLYVE-1 Sf9 recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
34,574 Da
NCBI Official Full Name
lymphatic vessel endothelial hyaluronic acid receptor 1
NCBI Official Synonym Full Names
lymphatic vessel endothelial hyaluronan receptor 1
NCBI Official Symbol
Lyve1
NCBI Official Synonym Symbols
Xlkd1; Lyve-1; Crsbp-1; 1200012G08Rik
NCBI Protein Information
lymphatic vessel endothelial hyaluronic acid receptor 1; cell surface retention sequence binding protein-1; cell surface retention sequence-binding protein 1; extra cellular link domain-containing 1; extracellular link domain-containing protein 1; lymphatic vessel endothelial HA receptor-1; lymphatic vessel endothelial HA recptor-1
UniProt Protein Name
Lymphatic vessel endothelial hyaluronic acid receptor 1
Protein Family
UniProt Gene Name
Lyve1
UniProt Synonym Gene Names
Crsbp1; Xlkd1; LYVE-1; CRSBP-1
UniProt Entry Name
LYVE1_MOUSE
Uniprot Description
XLKD1: Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). May act as an hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes.
Protein type: Membrane protein, integral; Motility/polarity/chemotaxis
Cellular Component: membrane; integral to membrane; plasma membrane
Molecular Function: transmembrane receptor activity; hyaluronic acid binding
Biological Process: glycosaminoglycan catabolic process; transport; cell adhesion; signal transduction
Research Articles on mLYVE-1 Sf9
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Product Notes
The mLYVE-1 Sf9 lyve1 (Catalog #AAA142797) is a Recombinant Protein produced from Insect Cells and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Lymphatic Vessel Endothelial Hyaluronic Acid Receptor 1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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