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MD2/LY96 Recombinant Protein | LY96 recombinant protein
MD2/LY96 Protein, Mouse, Recombinant (hFc Tag)
Gene Names
Ly96; MD2; MD-2; ESOP-1
Purity
>95% as determined by SDS-PAGE
Synonyms
MD2/LY96; MD2/LY96 Protein; Mouse; Recombinant (hFc Tag); Mouse LY-96/ESOP-1 Protein (Fc Tag); ESOP-1 Protein; MD-2 Protein; MD2 Protein; lymphocyte antigen 96; LY96 recombinant protein
Host
HEK293 Cells
Purity/Purification
>95% as determined by SDS-PAGE
Form/Format
Lyophilized from sterile PBS, pH7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
Sequence
Met1-Asn160
Species
Mouse
Endotoxin
<1.0EU per ug of the protein as determined by the LAL method
Predicted N Terminal
Glu 19
Tag
C-human IgG1-Fc
Protein Construction
A DNA sequence encoding the mouse LY96 (Q9JHF9)(Met1-Asn160) was expressed with the Fc region of human IgG1 at the C-terminus.
Reconstitution
A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -20 degree C to -80 degree C. Store it under sterile conditions at -20 degree C to -80 degree C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid.
They are shipped out with blue ice.
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid.
They are shipped out with blue ice.
SDS-Page
SDS-Page
Related Product Information for LY96 recombinant protein
Background: LY96 (Lymphocyte Antigen 96, also known as ESOP-1) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. This gene encodes a protein that associates with toll-like receptor 4 on the cell surface and confers responsiveness to lipopolysaccharide (LPS), thus providing a link between the receptor and LPS signaling. LY-96 also cooperates with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria. It enhances the TLR4-dependent activation of NF-kappa-B. ESOP-1 has 16 amino acids, the sequence of which shows 64% identity with human ESOP-1/MD-2. ESOP-1 mRNA is highly expressed in the mouse embryos at 7.5 days after coitus. Diseases associated with LY96 include Melioidosis and Intestinal Botulism.
Product Categories/Family for LY96 recombinant protein
References
Shimazu R., et al.,(1999), MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4. J. Exp. Med. 189:1777-1782.Kato K., et al., (2000), ESOP-1, a secreted protein expressed in the hematopoietic, nervous, and reproductive systems of embryonic and adult mice.Blood 96:362-364.Schromm A.B., et al.,(2001), Molecular genetic analysis of an endotoxin nonresponder mutant cell line. A point mutation in a conserved region of MD-2 abolishes endotoxin-induced signaling.J. Exp. Med. 194:79-88.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
18,394 Da
NCBI Official Full Name
lymphocyte antigen 96 isoform A
NCBI Official Synonym Full Names
lymphocyte antigen 96
NCBI Official Symbol
Ly96
NCBI Official Synonym Symbols
MD2; MD-2; ESOP-1
NCBI Protein Information
lymphocyte antigen 96; ly-96; protein MD-2; myeloid differentiation factor-2; myeloid differentiation protein-2
UniProt Protein Name
Lymphocyte antigen 96
Protein Family
UniProt Gene Name
Ly96
UniProt Synonym Gene Names
Esop1; Md2; Ly-96
UniProt Entry Name
LY96_MOUSE
Research Articles on LY96
Similar Products
Product Notes
The LY96 ly96 (Catalog #AAA8123124) is a Recombinant Protein produced from HEK293 Cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Met1-Asn16 0. It is sometimes possible for the material contained within the vial of "MD2/LY96, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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