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Western Blot (WB) (LY96 Antibody (C-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the LY96 antibody detected the LY96 protein (arrow).)

Rabbit anti-Human LY96 Polyclonal Antibody | anti-Ly96 antibody

LY96, CT (LY96, ESOP1, MD2, Lymphocyte antigen 96, ESOP-1, Protein MD-2)

Gene Names
Ly96; MD2; MD-2; ESOP-1
Reactivity
Human
Applications
ELISA, Western Blot
Purity
Affinity Purified
Purified by Protein A affinity chromatography.
Synonyms
LY96; Polyclonal Antibody; CT (LY96; ESOP1; MD2; Lymphocyte antigen 96; ESOP-1; Protein MD-2); Anti -LY96; anti-Ly96 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Human
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Applicable Applications for anti-Ly96 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes
Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Immunogen
LY96 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 102-132 amino acids from the C-terminal region of human LY96.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(LY96 Antibody (C-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the LY96 antibody detected the LY96 protein (arrow).)

Western Blot (WB) (LY96 Antibody (C-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the LY96 antibody detected the LY96 protein (arrow).)
Related Product Information for anti-Ly96 antibody
This gene encodes a protein which associates with toll-like receptor 4 on the cell surface and confers responsiveness to lipopolysaccyaride (LPS), thus providing a link between the receptor and LPS signaling. Studies of the mouse ortholog suggest that this gene may be involved in endotoxin neutralization. Alternative splicing results in multiple transcript variants encoding different isoforms.
Product Categories/Family for anti-Ly96 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
18,394 Da
NCBI Official Full Name
lymphocyte antigen 96 isoform B
NCBI Official Synonym Full Names
lymphocyte antigen 96
NCBI Official Symbol
Ly96
NCBI Official Synonym Symbols
MD2; MD-2; ESOP-1
NCBI Protein Information
lymphocyte antigen 96; ly-96; protein MD-2; myeloid differentiation factor-2; myeloid differentiation protein-2
UniProt Protein Name
Lymphocyte antigen 96
Protein Family
UniProt Gene Name
Ly96
UniProt Synonym Gene Names
Esop1; Md2; Ly-96
UniProt Entry Name
LY96_MOUSE

Uniprot Description

LY96: a secreted protein that binds to the extracellular domains of TLR2 and TLR4. Cooperates with TLR4 in the innate immune response to bacterial lipopolysaccharide (LPS), and with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria. Enhances TLR4-dependent activation of NF-kappa-B. Cells expressing both LY96 and TLR4, but not TLR4 alone, respond to LPS. Heterogeneous homopolymer formed from homodimers; disulfide-linked. Belongs to the lipopolysaccharide (LPS) receptor complex, a multi-protein complex containing at least CD14, LY96 and TLR4. Ligand binding induces interaction with TLR4 and oligomerization of the complex.

Protein type: Secreted, signal peptide; Secreted

Cellular Component: extracellular region; lipopolysaccharide receptor complex

Molecular Function: protein binding; lipopolysaccharide receptor activity

Biological Process: immune system process; detection of lipopolysaccharide; positive regulation of lipopolysaccharide-mediated signaling pathway; lipopolysaccharide-mediated signaling pathway; innate immune response; response to lipopolysaccharide; pattern recognition receptor signaling pathway; inflammatory response

Research Articles on Ly96

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Product Notes

The Ly96 ly96 (Catalog #AAA6001431) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The LY96, CT (LY96, ESOP1, MD2, Lymphocyte antigen 96, ESOP-1, Protein MD-2) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's LY96 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in Western Blot, ELISA Dilution: ELISA: 1:1,000 Western Blot: 1:100-500. Researchers should empirically determine the suitability of the Ly96 ly96 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LY96, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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