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Lymphocyte antigen 96 Recombinant Protein | Ly96 recombinant protein
Recombinant Mouse Lymphocyte antigen 96
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NCBI and Uniprot Product Information
Uniprot Description
LY96: a secreted protein that binds to the extracellular domains of TLR2 and TLR4. Cooperates with TLR4 in the innate immune response to bacterial lipopolysaccharide (LPS), and with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria. Enhances TLR4-dependent activation of NF-kappa-B. Cells expressing both LY96 and TLR4, but not TLR4 alone, respond to LPS. Heterogeneous homopolymer formed from homodimers; disulfide-linked. Belongs to the lipopolysaccharide (LPS) receptor complex, a multi-protein complex containing at least CD14, LY96 and TLR4. Ligand binding induces interaction with TLR4 and oligomerization of the complex.
Protein type: Secreted; Secreted, signal peptide
Cellular Component: extracellular region; intrinsic to plasma membrane; lipopolysaccharide receptor complex
Molecular Function: lipopolysaccharide receptor activity; protein binding
Biological Process: detection of lipopolysaccharide; immune system process; inflammatory response; innate immune response; lipopolysaccharide-mediated signaling pathway; positive regulation of lipopolysaccharide-mediated signaling pathway; positive regulation of tumor necrosis factor production; response to lipopolysaccharide; toll-like receptor 4 signaling pathway
Research Articles on Ly96
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Product Notes
The Ly96 ly96 (Catalog #AAA1375411) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 19-160aa; Full Length. The amino acid sequence is listed below: EKQQWFCNSS DAIISYSYCD HLKFPISISS EPCIRLRGTN GFVHVEFIPR GNLKYLYFNL FISVNSIELP KRKEVLCHGH DDDYSFCRAL KGETVNTSIP FSFEGILFPK GHYRCVAEAI AGDTEEKLFC LNFTIIHRRD VN. It is sometimes possible for the material contained within the vial of "Lymphocyte antigen 96, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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