Galectin 3 (GAL3) Recombinant Protein | GAL3 recombinant protein

Recombinant Galectin 3 (GAL3)

Cat. Num. AAA2011952

• Gene Names: Lgals3; GBP; L-34; gal3; Mac-2
• Applications: SDS-Page, Western Blot, ELISA, Immunoprecipitation
• Purity: > 95%
• Synonyms: Galectin 3 (GAL3); Recombinant Galectin 3 (GAL3); GAL3 recombinant protein

• Host: E Coli
• Purity/Purification: > 95%
• Form/Format: Supplied as lyophilized form in PBS,pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Sequence: The target protein is fused with N-terminal His-Tag, its sequence is listed below.; MGHHHHHHSGSEF-ADSFSLNDA LAGSGNPNPQ GYPGAWGNQP GAGGYPGAAY PGAYPGQAPP GAYPGQAPPG AYPGQAPPSA YPGPTAPGAY PGPTAPGAYP GSTAPGAFPG QPGAPGAYPS APGGYPAAGP YGVPAGPLTV PYDLPLPGGV MPRMLITIMG TVKPNANRIV LDFRRGNDVA FHFNPRFNEN NRRVIVCNTK QDNNWGKEER QSAFPFESGK PFKIQVLVEA DHFKVAVNDA HLLQYNHRMK NLREISQLGI SGDITLTSAN HAMI
• Sequence Length: 264

• Applicable Applications for GAL3 recombinant protein: SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)
• Organism: Mus musculus (Mouse)
• Expression System: Prokaryotic expression
• Residues: Ala2 ~Ile264 (Accession # Q8C253) with N-terminal His-Tag
• Endotoxin Level: <1.0EU per 1ug (determined by the LAL method)
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Preparation and Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.; Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.

SDS-Page

NCBI and Uniprot Product Information

• NCBI GI #: 225543163
• NCBI GeneID: 16854
• NCBI Accession #: NP_001139425.1
• NCBI GenBank Nucleotide #: NM_001145953.1
• UniProt Accession #: Q8C253; P16110
• Molecular Weight: 28.8kDa
• NCBI Official Full Name: galectin-3
• NCBI Official Synonym Full Names: lectin, galactose binding, soluble 3
• NCBI Official Symbol: Lgals3
• NCBI Official Synonym Symbols: GBP; L-34; gal3; Mac-2
• NCBI Protein Information: galectin-3; gal-3; CBP 35; lectin L-29; 35 kDa lectin; mac-2 antigen; igE-binding protein; laminin-binding protein; galactose-specific lectin 3; L-34 galactoside-binding lectin; carbohydrate-binding protein 35
• UniProt Protein Name: Galectin
• UniProt Gene Name: Lgals3
• UniProt Entry Name: Q8C253_MOUSE

Uniprot Description

Galectin-3: galactose-specific lectin which binds IgE. Expressed at a high level in the colonic epithelium. Also abundant in activated macrophages.

Protein type: Extracellular matrix; Motility/polarity/chemotaxis; Cell surface

Cellular Component: spliceosome; extracellular matrix; extracellular space; proteinaceous extracellular matrix; cell surface; membrane; cytoplasm; mitochondrial inner membrane; extracellular region; immunological synapse; nucleus; external side of plasma membrane

Molecular Function: monosaccharide binding; protein binding; advanced glycation end-product receptor activity; laminin binding; IgE binding; carbohydrate binding; chemoattractant activity; disaccharide binding

Biological Process: neutrophil chemotaxis; extracellular matrix organization and biogenesis; immune system process; positive regulation of serotonin secretion; RNA splicing; negative regulation of endocytosis; regulation of T cell proliferation; negative regulation of T cell receptor signaling pathway; signal transduction; macrophage chemotaxis; monocyte chemotaxis; positive regulation of angiogenesis; positive chemotaxis; positive regulation of cell proliferation; eosinophil chemotaxis; innate immune response; mRNA processing; cell differentiation; skeletal development; negative regulation of apoptosis