Human linker for activation of T cells family, member 2 ELISA Kit | LAT2 elisa kit
Human Linker for activation of T-cells family member 2, LAT2 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene is one of the contiguous genes at 7q11.23 commonly deleted in Williams syndrome, a multisystem developmental disorder. This gene consists of at least 14 exons, and its alternative splicing generates 3 transcript variants, all encoding the same protein. [provided by RefSeq, Jul 2008]
Uniprot Description
LAB: linker for activation of B cells (LAB) is an adaptor protein. B cell antigen receptor signaling leads to its phosphorylation and interaction with the adaptor protein Grb2. Decreased expression leads to a reduction in BCR-mediated calcium flux and Erk activation. Localized to lipid rafts.
Protein type: Adaptor/scaffold; Membrane protein, integral
Chromosomal Location of Human Ortholog: 7q11.23
Cellular Component: mast cell granule; integral to membrane; plasma membrane; lipid raft
Molecular Function: protein binding; SH2 domain binding
Biological Process: B cell receptor signaling pathway; B cell activation; calcium-mediated signaling; innate immune response; mast cell degranulation
Research Articles on LAT2
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Product Notes
The Human LAT2 lat2 (Catalog #AAA9324540) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9324540 ELISA Kit recognizes Human LAT2. It is sometimes possible for the material contained within the vial of "linker for activation of T cells family, member 2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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