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Leucyl tRNA Synthetase 2, Mitochondrial Recombinant Protein | LARS2 recombinant protein

Recombinant Leucyl tRNA Synthetase 2, Mitochondrial (LARS2)

Gene Names
LARS2; HLASA; LEURS; PRLTS4; mtLeuRS
Applications
SDS-Page, Western Blot
Purity
>90%
Synonyms
Leucyl tRNA Synthetase 2; Mitochondrial; Recombinant Leucyl tRNA Synthetase 2; Mitochondrial (LARS2); LEURS; Leucine tRNA Ligase 2; Mitocondrial; Leucyl-tRNA synthetase; LARS2 recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
>90%
Form/Format
Freeze-dried powder
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Sequence Positions
Leu677~Asp903
Sequence Length
903
Applicable Applications for LARS2 recombinant protein
Positive Control, Immunogen, SDS-PAGE, Western Blot (WB)
Source
Prokaryotic expression
Species
Human
Tag
N-terminal His Tag
Subcellular Location
Mitochondrion
Isoelectric Point
7.9
Reconstitution
Reconstitute in PBS or others.
Preparation and Storage
Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months. Avoid repeated freeze/thaw cycles.
Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Product Categories/Family for LARS2 recombinant protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
Predicted Molecular Mass: 29.1kDa
Accurate Molecular Mass: 29kDa
NCBI Official Full Name
Probable leucine--tRNA ligase, mitochondrial
NCBI Official Synonym Full Names
leucyl-tRNA synthetase 2, mitochondrial
NCBI Official Symbol
LARS2
NCBI Official Synonym Symbols
HLASA; LEURS; PRLTS4; mtLeuRS
NCBI Protein Information
probable leucine--tRNA ligase, mitochondrial
UniProt Protein Name
Probable leucine--tRNA ligase, mitochondrial
UniProt Gene Name
LARS2
UniProt Synonym Gene Names
KIAA0028; LeuRS
UniProt Entry Name
SYLM_HUMAN

NCBI Description

This gene encodes a class 1 aminoacyl-tRNA synthetase, mitochondrial leucyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. [provided by RefSeq, Jul 2008]

Uniprot Description

LARS2: a class 1 aminoacyl-tRNA synthetase, mitochondrial leucyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. [provided by RefSeq, Jul 2008]

Protein type: Translation; Amino Acid Metabolism - valine, leucine and isoleucine biosynthesis; Mitochondrial; Ligase; EC 6.1.1.4

Chromosomal Location of Human Ortholog: 3p21.3

Cellular Component: mitochondrion; mitochondrial matrix; cytosol

Molecular Function: leucine-tRNA ligase activity; ATP binding

Biological Process: leucyl-tRNA aminoacylation; tRNA aminoacylation for protein translation; regulation of translational fidelity; gene expression

Disease: Perrault Syndrome 4

Research Articles on LARS2

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Product Notes

The LARS2 lars2 (Catalog #AAA2123634) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is Leu677~Asp903. AAA Biotech's Leucyl tRNA Synthetase 2, Mitochondrial can be used in a range of immunoassay formats including, but not limited to, Positive Control, Immunogen, SDS-PAGE, Western Blot (WB). Researchers should empirically determine the suitability of the LARS2 lars2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Leucyl tRNA Synthetase 2, Mitochondrial, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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