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Western Blot (WB) (Western blot analysis of extracts from MCF7 cells, using LARS2 Antibody. The lane on the left was treated with blocking peptide.)

Rabbit LARS2 Polyclonal Antibody | anti-LARS2 antibody

LARS2 Antibody

Gene Names
LARS2; HLASA; LEURS; PRLTS4; mtLeuRS
Reactivity
Human
Predicted: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
Applications
Western Blot
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
LARS2; Polyclonal Antibody; LARS2 Antibody; HLASA; KIAA0028; LARS 2; Lars2; Leucine translase; Leucine tRNA ligase 2; Leucine tRNA ligase 2 mitocondrial; Leucine tRNA ligase; Leucine--tRNA ligase; Leucyl tRNA synthetase 2; Leucyl tRNA synthetase 2 mitochondrial; LeuRS; MGC26121; mtLeuRS; PRLTS4; Probable leucyl-tRNA synthetase; mitochondrial; SYLM_HUMAN; anti-LARS2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Predicted: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
Clonality
Polyclonal
Isotype
IgG
Specificity
LARS2 Antibody detects endogenous levels of LARS2.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid; Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
903
Applicable Applications for anti-LARS2 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
A synthesized peptide derived from human LARS2.
Tissue Specificity
Ubiquitously expressed, but highest expression in tissues with high metabolic rates, such as skeletal muscle, heart, and kidney.
Fragment
Fab Fragment
Conjugate
Unconjugated
Subcellular Location
Mitochondrion
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.

Western Blot (WB)

(Western blot analysis of extracts from MCF7 cells, using LARS2 Antibody. The lane on the left was treated with blocking peptide.)

Western Blot (WB) (Western blot analysis of extracts from MCF7 cells, using LARS2 Antibody. The lane on the left was treated with blocking peptide.)
Related Product Information for anti-LARS2 antibody
Description: ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu).

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
Observed: 102 kDa
Predicted: 102 kDa
NCBI Official Full Name
Probable leucine--tRNA ligase, mitochondrial
NCBI Official Synonym Full Names
leucyl-tRNA synthetase 2, mitochondrial
NCBI Official Symbol
LARS2
NCBI Official Synonym Symbols
HLASA; LEURS; PRLTS4; mtLeuRS
NCBI Protein Information
probable leucine--tRNA ligase, mitochondrial
UniProt Protein Name
Probable leucine--tRNA ligase, mitochondrial
UniProt Gene Name
LARS2
UniProt Synonym Gene Names
KIAA0028; LeuRS
UniProt Entry Name
SYLM_HUMAN

NCBI Description

This gene encodes a class 1 aminoacyl-tRNA synthetase, mitochondrial leucyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. [provided by RefSeq, Jul 2008]

Uniprot Description

LARS2: a class 1 aminoacyl-tRNA synthetase, mitochondrial leucyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. [provided by RefSeq, Jul 2008]

Protein type: Translation; Amino Acid Metabolism - valine, leucine and isoleucine biosynthesis; Mitochondrial; Ligase; EC 6.1.1.4

Chromosomal Location of Human Ortholog: 3p21.3

Cellular Component: mitochondrion; mitochondrial matrix; cytosol

Molecular Function: leucine-tRNA ligase activity; ATP binding

Biological Process: leucyl-tRNA aminoacylation; tRNA aminoacylation for protein translation; regulation of translational fidelity; gene expression

Disease: Perrault Syndrome 4

Research Articles on LARS2

Similar Products

Product Notes

The LARS2 lars2 (Catalog #AAA9611872) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The LARS2 Antibody reacts with Human Predicted: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus and may cross-react with other species as described in the data sheet. AAA Biotech's LARS2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the LARS2 lars2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LARS2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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