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Cytokeratin 19 Recombinant Protein | KRT19 recombinant protein

Cytokeratin 19 protein

Applications
Control
Synonyms
Cytokeratin 19; Cytokeratin 19 protein; Cytokeratin-19 protein; Cytokeratin-19; Keratin K19 protein; KRT19 recombinant protein
Ordering
For Research Use Only!
Host
Human
Form/Format
Lyophilized. 250 ug - reconstitute with 175 ul distilled water (final volume 250 ul), or 100ug - reconstitute with 70 ul distilled water (final volume 100 ul). Final solution: 30 mM Tris/HCI pH 8, 9.5 M urea, 2 mM DTT, 2 mM EDTA, and 10 mM methylammonium
Sequence Length
9
Applicable Applications for KRT19 recombinant protein
Control
Application Notes
Protein standard in 1D and 2D SDS gel electrophoresis, Immunoassays, Immunization
Protein Type
Recombinant
Biological Significance
Cytokeratins are proteins of keratin-containing intermediate filaments found in the intracytoplasmic cytoskeleton of epithelial tissue. Cytokeratin represents an excellent marker for the discrimination of specific subtypes of adenocarcinoma. Keratin, type I cytoskeletal 19 also known as cytokeratin-19 (CK-19) or keratin-19 (K19) is a protein that in humans is encoded by the KRT19 gene. Keratin 19 is a type I keratin.
Expression System
E Coli
Preparation and Storage
Store at 4 degree C until reconstitution. Following reconstitution aliquot and freeze at -20 degree C for long term storage. Avoid repeated freeze-thaw cycles.
Related Product Information for KRT19 recombinant protein
Purified recombinant Human Cytokeratin 19 protein
Product Categories/Family for KRT19 recombinant protein

NCBI and Uniprot Product Information

NCBI GI #
Molecular Weight
44,106 Da
NCBI Official Full Name
cytokeratin 19, partial
UniProt Protein Name
Keratin, type I cytoskeletal 19
Protein Family
UniProt Gene Name
KRT19
UniProt Synonym Gene Names
CK-19; K19
UniProt Entry Name
K1C19_HUMAN

Uniprot Description

K19: a type I cytoskeletal keratin. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Keratin 19 differs from all other IF proteins in lacking the C-terminal tail domain. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis.

Protein type: Cytoskeletal

Chromosomal Location of Human Ortholog: 17q21.2

Cellular Component: dystrophin-associated glycoprotein complex; costamere; intermediate filament; Z disc; sarcolemma

Molecular Function: protein binding; structural constituent of cytoskeleton; structural constituent of muscle; protein complex binding

Biological Process: viral reproduction; response to estrogen stimulus; sarcomere organization

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Product Notes

The Cytokeratin 19 krt19 (Catalog #AAA538141) is a Recombinant Protein produced from Human and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Cytokeratin 19 can be used in a range of immunoassay formats including, but not limited to, Control. Protein standard in 1D and 2D SDS gel electrophoresis, Immunoassays, Immunization. Researchers should empirically determine the suitability of the Cytokeratin 19 krt19 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Cytokeratin 19, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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