SDS-Page
(3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain )
Kallikrein 10 Recombinant Protein | KLK10 recombinant protein
Recombinant Kallikrein 10
Applications
SDS-Page
Purity
>90% by SDS-PAGE
Synonyms
Kallikrein 10; Recombinant Kallikrein 10; Kallikrein-10; NES1; PRSSL1; KLK10 recombinant protein
Host
Baculovirus
Purity/Purification
>90% by SDS-PAGE
Form/Format
Liquid; In 20mM Tris-HCl (pH 8.0), Containing 0.15M NaCl, 1mM DTT, 30% Glycerol.
Concentration
0.5mg/ml (determined by Absorbance at 280nm) (varies by lot)
Sequence Positions
34-276aa
Sequence
ADPALLPQND TRLDPEAYGS PCARGSQPWQ VSLFNGLSFH CAGVLVDQSW VLTAAHCGNK PLWARVGDDH LLLLQGEQLR RTTRSVVHPK YHQGSGPILP RRTDEHDLML LKLARPVVLG PRVRALQLPY RCAQPGDQCQ VAGWGTTAAR RVKYNKGLTC SSITILSPKE CEVFYPGVVT NNMICAGLDR GQDPCQSDSG GPLVCDETLQ GILSWGVYPC GSAQHPAVYT QICKYMSWIN KVIRSNHHHH HH
Sequence Length
276
Applicable Applications for KLK10 recombinant protein
SDS-PAGE
Species
Human
Endotoxin
<1.0 EU per 1ug of protein (determined by LAL method)
Tag
His-Tag
Preparation and Storage
Can be stored at 2 degree C to 8 degree C for 1 week. For long term storage, aliquot and store at -20 degree C to -80 degree C. Avoid repeated freezing and thawing cycles.
SDS-Page
(3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain )
SDS-Page
(3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain )
Related Product Information for KLK10 recombinant protein
KLK10, also known as kallikrein-10, is belong to the subgroup of serine proteases encompassing fifteen homologous members. This protein is widely expressed in normal human organs, for example breast, prostate, thyroid, testis, ovary, and gastrointestinal tract. Interestingly, it is highly expressed in the islets of Langerhans in human pancreas. Also, it is detectable in many biological fluids, including milk, seminal plasma, amniotic fluid, serum, and cerebrospinal fluid. In spite of its unknown physiological functions, the implications of KLK10 in various diseases have been explored. Early studies have shown that this expression is dramatically down-regulated in breast and testicular germ-cell tumors. It is secreted and may play a role in suppression of tumorigenesis in breast. Recombinant human KLK10, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Categories/Family for KLK10 recombinant protein
References
Petraki CD., et al, (2002) J. Histochem. Cytochem. 50:1247-1261.;Luo LY., et al. (2002) Br. J. Cancer. 86:1790-1796.
NCBI and Uniprot Product Information
NCBI GI #
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
27.8 kDa (252aa)
NCBI Official Full Name
kallikrein-10 preproprotein
UniProt Protein Name
Kallikrein-10
Protein Family
UniProt Gene Name
KLK10
UniProt Synonym Gene Names
NES1; PRSSL1
UniProt Entry Name
KLK10_HUMAN
Uniprot Description
KLK10: Has a tumor-suppressor role for NES1 in breast and prostate cancer. Belongs to the peptidase S1 family. Kallikrein subfamily.
Protein type: Tumor suppressor; Secreted; Secreted, signal peptide; EC 3.4.21.-; Protease
Chromosomal Location of Human Ortholog: 19q13
Cellular Component: extracellular region
Molecular Function: serine-type peptidase activity; serine-type endopeptidase activity
Biological Process: proteolysis; cell cycle
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Product Notes
The KLK10 klk10 (Catalog #AAA201099) is a Recombinant Protein produced from Baculovirus and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 34-276aa. AAA Biotech's Kallikrein 10 can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE. Researchers should empirically determine the suitability of the KLK10 klk10 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: ADPALLPQND TRLDPEAYGS PCARGSQPWQ VSLFNGLSFH CAGVLVDQSW VLTAAHCGNK PLWARVGDDH LLLLQGEQLR RTTRSVVHPK YHQGSGPILP RRTDEHDLML LKLARPVVLG PRVRALQLPY RCAQPGDQCQ VAGWGTTAAR RVKYNKGLTC SSITILSPKE CEVFYPGVVT NNMICAGLDR GQDPCQSDSG GPLVCDETLQ GILSWGVYPC GSAQHPAVYT QICKYMSWIN KVIRSNHHHH HH. It is sometimes possible for the material contained within the vial of "Kallikrein 10, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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