KLF12 recombinant protein

KLF12, 1-402aa, Human, His tag, E Coli (Denatured)

Cat. Num. AAA206014

• Gene Names: KLF12; AP2REP; AP-2rep; HSPC122
• Applications: SDS-Page
• Purity: > 85% by SDS-PAGE
• Synonyms: KLF12; 1-402aa; Human; His tag; E Coli (Denatured); Krueppel-like factor 12; AP-2rep; AP2REP; HSPC122; KLF12 recombinant protein

• Host: E Coli
• Purity/Purification: > 85% by SDS-PAGE
• Form/Format: Liquid. 20mM Tris-HCl Buffer (pH 8.0) containing 10% glycerol 0.4M urea
• Concentration: 0.5 mg/ml (determined by Bradford assay) (varies by lot)
• Sequence: MGSSHHHHHH SSGLVPRGSH MGSMNIHMKR KTIKNINTFE NRMLMLDGMP AVRVKTELLE SEQGSPNVHN YPDMEAVPLL LNNVKGEPPE DSLSVDHFQT QTEPVDLSIN KARTSPTAVS SSPVSMTASA SSPSSTSTSS SSSSRLASSP TVITSVSSAS SSSTVLTPGP LVASASGVGG QQFLHIIHPV PPSSPMNLQS NKLSHVHRIP VVVQSVPVVY TAVRSPGNVN NTIVVPLLED GRGHGKAQMD PRGLSPRQSK SDSDDDDLPN VTLDSVNETG STALSIARAV QEVHPSPVSR VRGNRMNNQK FPCSISPFSI ESTRRQRRSE SPDSRKRRIH RCDFEGCNKV YTKSSHLKAH RRTHTGEKPY KCTWEGCTWK FARSDELTRH YRKHTGVKPF KCADCDRSFS RSDHLALHRR RHMLV
• Sequence Length: 402

• Applicable Applications for KLF12 recombinant protein: SDS-PAGE
• Antigen Species: Human
• Tag Information: His-tag
• Preparation and Storage: Can be stored at 4 degree C short term (1-2 weeks).; For long term storage, aliquot and store at -20 degree C or -70 degree C.; Avoid repeated freezing and thawing cycles.

SDS-Page

Related Product Information for KLF12 recombinant protein

KLF12, as known as Krueppel-like factor 12, is a member of the Kruppel-like zinc finger protein family and can repress expression of the AP-2 alpha gene by binding to a specific site in the AP-2 alpha gene promoter. Activator protein-2 alpha (AP-2 alpha) is a developmentally-regulated transcription factor and important regulator of gene expression during vertebrate development and carcinogenesis. Repression by the encoded protein requires binding with a corepressor, CtBP1. Two transcript variants encoding different isoforms have been found for this gene.cers. Recombinant human KLF12 protein, fused to His-tag at N-terminus, was expressed in E Coli.

Product Categories/Family for KLF12 recombinant protein

Epigenomics (Transcription & Translation)

References

Roth C. et al. (1996) Genomics. 63:384-390.; Schuierer M. et al. (2001) J Biol Chem. 276:27944-27949.

NCBI and Uniprot Product Information

• NCBI GI #: 21071074
• NCBI GeneID: 11278
• NCBI Accession #: NP_009180
• NCBI GenBank Nucleotide #: NM_007249.4
• UniProt Accession #: Q9Y4X4; Q5VZM7; Q9UHZ0; A8K5T2; L0R3J4
• Molecular Weight: 46.6 kDa (425aa)
• NCBI Official Full Name: Krueppel-like factor 12
• NCBI Official Synonym Full Names: Kruppel like factor 12
• NCBI Official Symbol: KLF12
• NCBI Official Synonym Symbols: AP2REP; AP-2rep; HSPC122
• NCBI Protein Information: Krueppel-like factor 12
• UniProt Protein Name: Krueppel-like factor 12
• Protein Family: Krueppel-like factor
• UniProt Gene Name: KLF12
• UniProt Synonym Gene Names: AP2REP

NCBI Description

Activator protein-2 alpha (AP-2 alpha) is a developmentally-regulated transcription factor and important regulator of gene expression during vertebrate development and carcinogenesis. The protein encoded by this gene is a member of the Kruppel-like zinc finger protein family and can repress expression of the AP-2 alpha gene by binding to a specific site in the AP-2 alpha gene promoter. Repression by the encoded protein requires binding with a corepressor, CtBP1. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

Confers strong transcriptional repression to the AP-2-alpha gene. Binds to a regulatory element (A32) in the AP-2-alpha gene promoter.