Rat KH-type splicing regulatory protein ELISA Kit | KHSRP elisa kit
Rat Far upstream element-binding protein 2, KHSRP ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
binds to the microtubule-associated protein 2 (Map2) 3 dendritic targeting element; may play a role in nucleocytoplasmic mRNA targeting [RGD, Feb 2006]
Uniprot Description
KHSRP: an RNA binding and processing protein that binds to the dendritic targeting element and may play a role in mRNA trafficking. Part of a ternary complex that binds to the downstream control sequence (DCS) of the pre-mRNA. Mediates exon inclusion in transcripts that are subject to tissue-specific alternative splicing. May interact with single-stranded DNA from the far-upstream element (FUSE). May activate gene expression. Also involved in degradation of inherently unstable mRNAs that contain AU-rich elements (AREs) in their 3' untranslated regions, possibly by recruiting degradation machinery to ARE-containing mRNAs. Interacts with APC which is part of the apolipoprotein B mRNA editing enzyme complex. The interaction is not required for activity of the catalytic component, APOBEC1, but may confer stability on the complex.
Protein type: RNA-binding
Cellular Component: nucleoplasm; membrane; cell soma; stress granule; cytoplasm; dendrite; nucleus
Molecular Function: mRNA binding; protein binding; DNA binding; mRNA 3'-UTR binding
Biological Process: mRNA transport; regulation of transcription, DNA-dependent; transcription, DNA-dependent; RNA splicing; mRNA catabolic process; mRNA processing
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Product Notes
The Rat KHSRP khsrp (Catalog #AAA9342886) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9342886 ELISA Kit recognizes Rat KHSRP. It is sometimes possible for the material contained within the vial of "KH-type splicing regulatory protein, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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