KCT2 Recombinant Protein | C5orf15 recombinant protein

KCT2 Protein, Human, Recombinant (His Tag)

Cat. Num. AAA8121538

• Gene Names: C5orf15; KCT2; HTGN29
• Purity: >95% as determined by SDS-PAGE
• Synonyms: KCT2; KCT2 Protein; Human; Recombinant (His Tag); Human KCT2/C5orf15 Protein (His Tag); HTGN29 Protein; chromosome 5 open reading frame 15; C5orf15 recombinant protein

• Host: HEK293 Cells
• Purity/Purification: >95% as determined by SDS-PAGE
• Form/Format: Lyophilized from sterile PBS, pH7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
• Sequence: Met1-Asp196

• Species: Human
• Endotoxin: <1.0EU per ug of the protein as determined by the LAL method
• Predicted N Terminal: Arg 50
• Tag: C-His
• Protein Construction: A DNA sequence encoding the human C5orf15 (NP_064584.1)(Met1-Asp196) was expressed with a C-terminal polyhistidine tag.
• Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
• Preparation and Storage: Samples are stable for up to twelve months from date of receipt at -20 degree C to -80 degree C. Store it under sterile conditions at -20 degree C to -80 degree C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.; In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid.; They are shipped out with blue ice.

SDS-Page

Related Product Information for C5orf15 recombinant protein

Background: C5orf15 (Chromosome 5 Open Reading Frame 15, also known as KCT2) is a Protein Coding gene. KCT2 gene maps to human chromosome 5q31.1 and is conserved in human, chimpanzee, cow, rat, and chicken. KCT2 is a 265 amino acid single-pass type I membrane protein that is widely expressed in the thyroid, kidney, and other tissues. Chromosome 5 is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Chromosome 5 contains 181 million base pairs and comprises nearly 6% of the human genome. Diseases associated with C5orf15 include Arrhythmogenic Right Ventricular Dysplasia, Familial, 5, and Amyotrophic Lateral Sclerosis 11.

References

Bonkobara M., et al.,(2003), Identification of novel genes for secreted and membrane-anchored proteins in human keratinocytes. Br. J. Dermatol. 148:654-664.Yu W, et al., (1997), Large-scale concatenation cDNA sequencing. Genome Res. 7(4):353-8.Ota T., et al.,(2004), Complete sequencing and characterization of 21,243 full-length human cDNAs.Nat. Genet. 36:40-45.

NCBI and Uniprot Product Information

• NCBI GI #: 9910278
• NCBI GeneID: 56951
• NCBI Accession #: NP_064584.1
• NCBI GenBank Nucleotide #: NM_020199.2
• UniProt Accession #: Q8NC54; Q9NRG2; B2RD10; D3DQ92
• Molecular Weight: 29,235 Da
• NCBI Official Full Name: keratinocyte-associated transmembrane protein 2
• NCBI Official Synonym Full Names: chromosome 5 open reading frame 15
• NCBI Official Symbol: C5orf15
• NCBI Official Synonym Symbols: KCT2; HTGN29
• NCBI Protein Information: keratinocyte-associated transmembrane protein 2; keratinocytes associated transmembrane protein 2
• UniProt Protein Name: Keratinocyte-associated transmembrane protein 2
• UniProt Gene Name: KCT2
• UniProt Synonym Gene Names: C5orf15; HTGN29
• UniProt Entry Name: KCT2_HUMAN