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ATP-sensitive inward rectifier potassium channel 1 (Kcnj1) Recombinant Protein | Kcnj1 recombinant protein

Recombinant Mouse ATP-sensitive inward rectifier potassium channel 1 (Kcnj1)

Gene Names
Kcnj1; ROMK; Romk2; Kir1.1
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
ATP-sensitive inward rectifier potassium channel 1 (Kcnj1); Recombinant Mouse ATP-sensitive inward rectifier potassium channel 1 (Kcnj1); Kcnj1 recombinant protein
Ordering
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-372
Sequence
MFKHLRRWFVTHIFGRSRQRARLVSKDGRCNIEFGNVDAQSRFIFFVDIWTTVLDLKWRYKMTVFITAFLGSWFLFGLLWYVVAYVHKDLPEFYPPDNRTPCVENINGMTSAFLFSLETQVTIGYGFRFVTEQCATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRVANLRKSLLIGSHIYGKLLKTTITPEGETIILDQTNINFVVDAGNENLFFISPLTIYHIIDHNSPFFHMAAETLSQQDFELVVFLDGTVESTSATCQVRTSYIPEEVLWGYRFVPIVSKTKEGKYRVDFHNFGKTVEVETPHCAMCLYNEKDARARMKRGYDNPNFVLSEVDETDDTQM
Sequence Length
372
Species
Mus musculus (Mouse)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
Related Product Information for Kcnj1 recombinant protein
Kcnj1

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
42,776 Da
NCBI Official Full Name
ATP-sensitive inward rectifier potassium channel 1 isoform 2
NCBI Official Synonym Full Names
potassium inwardly-rectifying channel, subfamily J, member 1
NCBI Official Symbol
Kcnj1
NCBI Official Synonym Symbols
ROMK; Romk2; Kir1.1
NCBI Protein Information
ATP-sensitive inward rectifier potassium channel 1; inward rectifier K(+) channel Kir1.1; ATP-regulated potassium channel ROM-K; inwardly rectifying potassium channel ROMK-2; potassium channel, inwardly rectifying subfamily J member 1
UniProt Protein Name
ATP-sensitive inward rectifier potassium channel 1
UniProt Gene Name
Kcnj1
UniProt Entry Name
IRK1_MOUSE

Uniprot Description

ROMK: an inward rectifier-type potassium channel protein. Probably plays a major role in potassium homeostasis in the kidney. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. The channel is activated by internal ATP and can be blocked by external barium. High levels of expression in the kidney and pancreatic islets. Lower levels in skeletal muscle, pancreas, spleen, brain, heart and liver. Three alternatively spliced isoforms have been described.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Channel, potassium

Cellular Component: membrane; integral to plasma membrane; plasma membrane; integral to membrane

Molecular Function: potassium ion binding; phosphatidylinositol-4,5-bisphosphate binding; nucleotide binding; ATP-activated inward rectifier potassium channel activity; voltage-gated ion channel activity; inward rectifier potassium channel activity; peptide binding; ATP binding

Biological Process: potassium ion import; transport; tissue homeostasis; ion transport; kidney development; potassium ion transport; post-embryonic development; negative regulation of apoptosis

Research Articles on Kcnj1

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Product Notes

The Kcnj1 kcnj1 (Catalog #AAA1225747) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-372. The amino acid sequence is listed below: MFKHLRRWFV THIFGRSRQR ARLVSKDGRC NIEFGNVDAQ SRFIFFVDIW TTVLDLKWRY KMTVFITAFL GSWFLFGLLW YVVAYVHKDL PEFYPPDNRT PCVENINGMT SAFLFSLETQ VTIGYGFRFV TEQCATAIFL LIFQSILGVI INSFMCGAIL AKISRPKKRA KTITFSKNAV ISKRGGKLCL LIRVANLRKS LLIGSHIYGK LLKTTITPEG ETIILDQTNI NFVVDAGNEN LFFISPLTIY HIIDHNSPFF HMAAETLSQQ DFELVVFLDG TVESTSATCQ VRTSYIPEEV LWGYRFVPIV SKTKEGKYRV DFHNFGKTVE VETPHCAMCL YNEKDARARM KRGYDNPNFV LSEVDETDDT QM. It is sometimes possible for the material contained within the vial of "ATP-sensitive inward rectifier potassium channel 1 (Kcnj1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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