Human K (lysine) acetyltransferase 2A ELISA Kit | KAT2A elisa kit
Human Histone acetyltransferase KAT2A, KAT2A ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also functions as a repressor of NF-kappa-B (see MIM 164011) by promoting ubiquitination of the NF-kappa-B subunit RELA (MIM 164014) in a HAT-independent manner (Mao et al., 2009 [PubMed 19339690]).[supplied by OMIM, Sep 2009]
Uniprot Description
GCN5: an ubiquitous histone acetyltransferase that promotes transcriptional activation. Acetylation of histones gives a specific tag for epigenetic transcription activation. Has significant histone acetyltransferase activity with core histones, but not with nucleosome core particles. Interacts with P300, CBP, ADA2, and is a component of the TFTC-HAT complex. Two splice variant isoforms have been described.
Protein type: Acetyltransferase; EC 2.3.1.48
Chromosomal Location of Human Ortholog: 17q21
Cellular Component: nucleoplasm; extracellular space
Molecular Function: protein binding; histone acetyltransferase activity; histone deacetylase binding; transcription coactivator activity; chromatin binding; H3 histone acetyltransferase activity
Biological Process: transcription from RNA polymerase II promoter; somitogenesis; establishment and/or maintenance of chromatin architecture; viral reproduction; in utero embryonic development; multicellular organism growth; regulation of protein stability; metencephalon development; histone deubiquitination; regulation of transcription from RNA polymerase II promoter; chromatin remodeling; cell proliferation; telencephalon development; midbrain development; neural tube closure
Research Articles on KAT2A
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Product Notes
The Human KAT2A kat2a (Catalog #AAA9330976) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9330976 ELISA Kit recognizes Human KAT2A. It is sometimes possible for the material contained within the vial of "K (lysine) acetyltransferase 2A, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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