Irisin:Fc Recombinant Protein
Irisin:Fc, Recombinant, Human (Fibronectin Type III Domain-containing Protein 5, Fibronectin Type III Repeat-containing Protein 2, FNDC5)
Purity
Highly Purified>95% (SDS-PAGE)
Synonyms
Irisin:Fc; Recombinant; Human (Fibronectin Type III Domain-containing Protein 5; Fibronectin Type III Repeat-containing Protein 2; FNDC5); Irisin:Fc recombinant protein
Host
Human, HEK 293 cells
Purity/Purification
Highly Purified
>95% (SDS-PAGE)
>95% (SDS-PAGE)
Form/Format
Supplied as a lyophilized powder from PBS.
Concentration
~0.1 mg/ml (after reconstitution) (varies by lot)
Sequence
Irisin (human, aa 16-127 /mouse, aa 29-140) is fused at the C-terminus to the Fc portion of human IgG1.
Endotoxin
<0.1EU/ug (LAL)
Reconstitution
Reconstitute with 100ul dH2O. Further dilutions can be made in PBS, >0.1% BSA.
Species Homology
aa16-127 of human Irisin corresponds to aa29-140 of mouse Irisin. Irisin has 100% identity between mouse, rat, monkey and human.
Preparation and Storage
Lyophilized powder may be stored at -20 Deg. C. Stable for 12 months at -20 Deg. C. Reconstitute with sterile for dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 Deg. C. Reconstituted product is stable for 6 months at -20 Deg C. For maximum recovery of product, centrifuge the orignal vial after thawing and prior to removing the cap.
Related Product Information for Irisin:Fc recombinant protein
Irisin is a recently described exercise-induced hormone secreted by skeletal muscle in mice and humans. Irisin activates beige fat cells (beige cells have a gene expression pattern distinct from either white or brown fat and are preferentially sensitive to the polypeptide hormone Irisin). Irisin is cleaved from the type I membrane protein FNDC5 and improves systemic metabolism by increasing energy expenditure.
Product Categories/Family for Irisin:Fc recombinant protein
Similar Products
Product Notes
The Irisin:Fc (Catalog #AAA637146) is a Recombinant Protein produced from Human, HEK 293 cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Irisin (human, aa 16-127 /mouse, aa 29-140) is fused at the C-terminus to the Fc portion of human IgG1. It is sometimes possible for the material contained within the vial of "Irisin:Fc, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
