Typical Testing Data/Standard Curve (for reference only)
Mouse Iron-responsive element-binding protein 2 ELISA Kit | Ireb2 elisa kit
Mouse Iron-responsive element-binding protein 2 ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
NCBI and Uniprot Product Information
Uniprot Description
IREB2: RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'- UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA. Belongs to the aconitase/IPM isomerase family.
Protein type: Translation; RNA-binding
Cellular Component: cytoplasm; cytosol; endoplasmic reticulum; Golgi apparatus; mitochondrion
Molecular Function: 4 iron, 4 sulfur cluster binding; iron-responsive element binding; iron-sulfur cluster binding; metal ion binding; RNA binding; translation repressor activity
Biological Process: cellular iron ion homeostasis; erythrocyte homeostasis; intestinal absorption; iron ion homeostasis; iron ion transport; metabolic process; negative regulation of translation; post-embryonic development; protoporphyrinogen IX biosynthetic process; regulation of gene expression; regulation of translation
Research Articles on Ireb2
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Product Notes
The Mouse Ireb2 ireb2 (Catalog #AAA2883422) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2883422 ELISA Kit recognizes Mouse Ireb2. It is sometimes possible for the material contained within the vial of "Iron-responsive element-binding protein 2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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