Mouse IQ motif and Sec7 domain 2 ELISA Kit | IQSEC2 elisa kit

Mouse IQ motif and SEC7 domain-containing protein 2, IQSEC2 ELISA Kit

Cat. Num. AAA9341514

• Gene Names: Iqsec2; Brag1; mKIAA0522
• Reactivity: Mouse
• Synonyms: IQ motif and Sec7 domain 2; Mouse IQ motif and SEC7 domain-containing protein 2; IQSEC2 ELISA Kit; Mouse IQ motif and SEC7 domain-containing protein 2 (IQSEC2) ELISA kit; RP11-258C19.1; BRAG1; KIAA0522; brefeldin A resistant Arf-guanine nucleotide exchange factor 1; brefeldin A resistant Arf-guanine nucleotide exchange factor 1b; brefeldin A resistant Arf-guanine nucle; IQSEC2 elisa kit

• Reactivity: Mouse

• Preparation and Storage: Store all reagents at 2-8 degree C

NCBI and Uniprot Product Information

• NCBI GI #: 569011985
• NCBI GeneID: 245666
• NCBI Accession #: XP_006528908.1
• NCBI GenBank Nucleotide #: XM_006528845.1
• UniProt Accession #: Q5DU25; E9QK46
• Molecular Weight: 161,787 Da
• NCBI Official Full Name: IQ motif and SEC7 domain-containing protein 2 isoform X4
• NCBI Official Synonym Full Names: IQ motif and Sec7 domain 2
• NCBI Official Symbol: Iqsec2
• NCBI Official Synonym Symbols: Brag1; mKIAA0522
• NCBI Protein Information: IQ motif and SEC7 domain-containing protein 2
• UniProt Protein Name: IQ motif and SEC7 domain-containing protein 2
• Protein Family: IQ motif and SEC7 domain-containing protein
• UniProt Gene Name: Iqsec2
• UniProt Synonym Gene Names: Kiaa0522
• UniProt Entry Name: IQEC2_MOUSE

Uniprot Description

IQSEC2: Defects in IQSEC2 are the cause of mental retardation X- linked type 1 (MRX1). Mental retardation is characterized by significantly below average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. In contrast to syndromic or specific X-linked mental retardation which also present with associated physical, neurological and/or psychiatric manifestations, intellectual deficiency is the only primary symptom of non-syndromic X-linked mental retardation. Belongs to the BRAG family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: GEFs; GEFs, ARF

Cellular Component: cytoplasm; nucleus; cell junction

Molecular Function: protein binding; ARF guanyl-nucleotide exchange factor activity

Biological Process: regulation of ARF protein signal transduction; actin cytoskeleton organization and biogenesis; positive regulation of GTPase activity