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Spindle assembly checkpoint kinase (IPL1) Recombinant Protein | IPL1 recombinant protein

Recombinant Kluyveromyces lactis Spindle assembly checkpoint kinase (IPL1)

Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Spindle assembly checkpoint kinase (IPL1); Recombinant Kluyveromyces lactis Spindle assembly checkpoint kinase (IPL1); Spindle assembly checkpoint kinase; EC=2.7.11.1; Aurora kinase; IPL1 recombinant protein
Ordering
For Research Use Only!
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-361aa; full length protein
Sequence
MRPSLSRDAS DTGRRHSLLQ QSKLLSIRLS NAGKRPSLSR GHAHEKDSIT SSHHRLSTGPVNNNPRRSLM VKKPNTAHGT RVPILNDHND KFENMTLQDF EIGKILGKGK FGKVYCVKHRETGLICALKA MEKKEIVQYT IQKQFRREVE IQGSFKHKNL TQLYGFFYDE KRVYLLMEYVYYGELYKFLK NNGPLNETLA SYFVYQMANA LDYMHSKNIL HRDIKPENIL IGFNNTIKLTDFGWSVYNED GQKRKTLCGT IDYLSPELIK SREYNNKVDV WALGVLTYEL LVGSPPFEEDTKEMTYRRIL RCDLKFPLNV SPQARDLIVR LLQFEPSKRI PLSEVKSHAW IANNRGSWTDL
Sequence Length
361
Species
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
41,892 Da
NCBI Official Full Name
hypothetical protein
NCBI Official Symbol
KLLA0B02332g
NCBI Protein Information
hypothetical protein
UniProt Protein Name
Spindle assembly checkpoint kinase
UniProt Gene Name
IPL1
UniProt Entry Name
IPL1_KLULA

Uniprot Description

Required for high-fidelity chromosome segregation during the later part of each cell cycle. Acts in opposition to the phosphatase PP1. Has a role in attaching the kinetochores to the microtubules and ensuring that sister kinetochores connect to opposite poles. The promotion of bi-orientation is achieved by selectively detaching kinetochore-microtubule attachments that are not under tension. Phosphorylates histone H3 to form H3S10ph during mitosis and meiosis ().

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Product Notes

The IPL1 ipl1 (Catalog #AAA1359798) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-361aa; full length protein. The amino acid sequence is listed below: MRPSLSRDAS DTGRRHSLLQ QSKLLSIRLS NAGKRPSLSR GHAHEKDSIT SSHHRLSTGP VNNNPRRSLM VKKPNTAHGT RVPILNDHND KFENMTLQDF EIGKILGKGK FGKVYCVKHR ETGLICALKA MEKKEIVQYT IQKQFRREVE IQGSFKHKNL TQLYGFFYDE KRVYLLMEYV YYGELYKFLK NNGPLNETLA SYFVYQMANA LDYMHSKNIL HRDIKPENIL IGFNNTIKLT DFGWSVYNED GQKRKTLCGT IDYLSPELIK SREYNNKVDV WALGVLTYEL LVGSPPFEED TKEMTYRRIL RCDLKFPLNV SPQARDLIVR LLQFEPSKRI PLSEVKSHAW IANNRGSWTD L. It is sometimes possible for the material contained within the vial of "Spindle assembly checkpoint kinase (IPL1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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