Type II inositol 1,4,5-trisphosphate 5-phosphatase (Inpp5b) Recombinant Protein | Inpp5b recombinant protein

Recombinant Mouse Type II inositol 1,4,5-trisphosphate 5-phosphatase (Inpp5b), partial

• Gene Names: Inpp5b; 5PTase; INPP5P; AW260155
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Type II inositol 1; 4; 5-trisphosphate 5-phosphatase (Inpp5b); Recombinant Mouse Type II inositol 1; partial; Inpp5b recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 742

• Species: Mouse
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 30231213
• NCBI GeneID: 16330
• NCBI Accession #: NP_032411.3
• NCBI GenBank Nucleotide #: NM_008385.4
• UniProt Accession #: Q8K337; O54996; Q8CF65; Q91ZF8
• Molecular Weight: 84,888 Da
• NCBI Official Full Name: type II inositol 1,4,5-trisphosphate 5-phosphatase
• NCBI Official Synonym Full Names: inositol polyphosphate-5-phosphatase B
• NCBI Official Symbol: Inpp5b
• NCBI Official Synonym Symbols: 5PTase; INPP5P; AW260155
• NCBI Protein Information: type II inositol 1,4,5-trisphosphate 5-phosphatase
• UniProt Protein Name: Type II inositol 1,4,5-trisphosphate 5-phosphatase
• Protein Family: Type II inositol 1,4,5-trisphosphate 5-phosphatase
• UniProt Gene Name: Inpp5b
• UniProt Synonym Gene Names: 5PTase

NCBI Description

This gene encodes a member of the inositol polyphosphate-5-phosphatase (INPP5) family. This protein hydrolyzes the 5' phosphate from phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol-1,4,5-trisphosphate, which results in changes to multiple signaling pathways. This protein may be involved in protein trafficking and secretion. Homozygous knockout mice exhibit impaired spermatogenesis and male sterility. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Nov 2014]

Uniprot Description

Hydrolyzes phosphatidylinositol 4,5-bisphosphate (PtIns(4,5)P2) and the signaling molecule phosphatidylinositol 1,4,5-trisphosphate (PtIns(1,4,5)P3), and thereby modulates cellular signaling events.