Structure
VAL-083, inhibitor
VAL-083
Purity
98.00%
Synonyms
VAL-083; Dianhydrodulcitol; Dianhydrogalactitol; inhibitor
Purity/Purification
98.00%
Form/Format
Solid. Powder
Solubility
DMF: 100mg/mL (684.28mM)
H2O: 50mg/mL (342.14mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)
H2O: 50mg/mL (342.14mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C6H10O4
SMILES
O[C@H]([C@H](O)[C@]1(OC1)[H])[C@@]2([H])CO2
CAS Number
23261-20-3
Target & IC50
DNA Alkylator
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
-80 degree C for 2 years in solvent
Structure
Structure
Related Product Information for VAL-083, inhibitor
VAL-083 is an alkylating compound that creates N7 methylation on DNA. It also has antitumor activity.
Product Categories/Family for VAL-083, inhibitor
References
Kaiji Hu, et al. Abstract 811: VAL083, a novel N7 alkylating agent, surpasses NSC 362856 activity and inhibits cancer stem cells providing a new potential treatment,option for glioblastoma multiforme. Cancer Research. 2012 Mar 31-Apr 4.
Jiang X, et al. Dianhydrogalactitol, a potential multitarget agent, inhibits glioblastoma migration, invasion, and angiogenesis. Biomed Pharmacother. 2017 Jul;91:1065-1074.
Peng C, et al. 1,2:5,6-dianhydrogalactitol inhibits human glioma cell growth in vivo and in vitro by arresting the cell cycle at G2/M phase. Acta Pharmacol Sin. 2017 Apr;38(4):561-570.
Jiang X, et al. Dianhydrogalactitol, a potential multitarget agent, inhibits glioblastoma migration, invasion, and angiogenesis. Biomed Pharmacother. 2017 Jul;91:1065-1074.
Peng C, et al. 1,2:5,6-dianhydrogalactitol inhibits human glioma cell growth in vivo and in vitro by arresting the cell cycle at G2/M phase. Acta Pharmacol Sin. 2017 Apr;38(4):561-570.
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Product Notes
The VAL-083 (Catalog #AAA5755685) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "VAL-083, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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