Structure
Raltitrexed, Inhibitor
Raltitrexed
Purity
>98% (HPLC)
Synonyms
Raltitrexed; ZD1694; D1694; ICI-D1694; inhibitor
Purity/Purification
>98% (HPLC)
Suitability
DMSO: >=29mg/mL
Target
Nucleoside Antimetabolite/Analog
Receptor
Thymidylatesynthase
Chemical Name
L-Glutamic acid, N-[[5-[[(3, 4-dihydro-2-methyl-4-oxo-6-quinazolinyl)methyl]methylamino]-2-thienyl]carbonyl]
SMILES
O=C(O)[C@@H](NC(C1=CC=C(N(C)CC2=CC3=C(NC(C)=NC3=O)C=C2)S1)=O)CCC(O)=O
Molecular Formula
C21H22N4O6S
CAS Number
112887-68-0
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for Raltitrexed, inhibitor
A quinazoline antifolate thymidylate synthase (TS) inhibitor with Ki of 62nM; inhibits TS with IC50 of 2.5nM and L1210 tumor cell growth with IC50 of 8nM; acitve in vivo. Chemotherapeutic Agents Approved
Product Categories/Family for Raltitrexed, inhibitor
References
1. Jackman AL, et al. Cancer Res. 1991 Oct 15; 51 (20):5579-86.
2. Yin MB, et al. Cancer Res. 1992 Nov 1; 52 (21):5900-5.
3. Pressacco J, et al. Cancer Res. 1995 Apr 1; 55 (7):1505-8.
2. Yin MB, et al. Cancer Res. 1992 Nov 1; 52 (21):5900-5.
3. Pressacco J, et al. Cancer Res. 1995 Apr 1; 55 (7):1505-8.
Similar Products
Product Notes
The Raltitrexed (Catalog #AAA3600453) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Raltitrexed, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
