Structure
Otamixaban, Inhibitor
Otamixaban
Purity
>98% (HPLC)
Synonyms
Otamixaban; FXV-673; inhibitor
Purity/Purification
>98% (HPLC)
Suitability
10mM in DMSO
Target
Factor Xa
Receptor
Factor Xa
Chemical Name
Benzenepropanoic acid, 3-(aminoiminomethyl)-.alpha.-[(1R)-1-[[4-(1-oxido-4-pyridinyl)benzoyl]amino]ethyl]-, methyl ester, (.alpha.R)
SMILES
C[C@@H](NC(C1=CC=C(C2=CC=[N+]([O-])C=C2)C=C1)=O)[C@@H](CC3=CC=CC(C(N)=N)=C3)C(OC)=O
Molecular Formula
C25H26N4O4
CAS Number
193153-04-7
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for Otamixaban, inhibitor
A potent and selective factor Xa (FXa) inhibitor with Ki of 0.4nM; shows >1,000-fold selectivity over thrombin, activated protein C (aPC), plasmin, and tissue-plasminogen activator (t-PA); dose-dependently prolongs the time to vessel occlusion and inhibits thrombus formation in canine models of thrombosis.Thrombosis Phase 3 Discontinued
Product Categories/Family for Otamixaban, inhibitor
References
1. Guertin KR, et al. Bioorg Med Chem Lett. 2002 Jun 17; 12 (12):1671-4.
2. Chu V, et al. Thromb Res. 2001 Aug 15; 103 (4):309-24.
3. Rebello SS, et al. J Cardiovasc Pharmacol. 2001 Aug; 38 (2):288-97.
2. Chu V, et al. Thromb Res. 2001 Aug 15; 103 (4):309-24.
3. Rebello SS, et al. J Cardiovasc Pharmacol. 2001 Aug; 38 (2):288-97.
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Product Notes
The Otamixaban (Catalog #AAA3603026) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Otamixaban, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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