Structure
NSC23005 sodium, Inhibitor
NSC23005 sodium
Purity
>98% (HPLC)
Synonyms
NSC23005 sodium; NSC 23005 sodium; NSC-23005 sodium; p18-IN-40; inhibitor
Purity/Purification
>98% (HPLC)
Suitability
DMSO: 6.4mg/mL (Need ultrasonic)
Target
CDK
Receptor
p18INK4C
Chemical Name
Benzoic acid, 4-[(cyclohexylamino)sulfonyl]-, sodium salt(1:1)
SMILES
C1CCC(CC1)NS(=O)(=O)C2=CC=C(C=C2)C(=O)[O-].[Na+]
Molecular Formula
C13H16NNaO4S
CAS Number
1796596-46-7
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for NSC23005 sodium, inhibitor
A novel specific, effective p18 (p18INK4C) inhibitor that can selectively promote HSCs expansion with EC50 of 5.21nM; inhibits p18, and then activates CDK4/6, promotes HSCs expansion in both murine and human models; shows no activity in promoting the proliferation of leukemia cells, and no significant cytotoxicity toward 32D cells or HSCs.
Product Categories/Family for NSC23005 sodium, inhibitor
References
1. Xie XQ, et al. Sci Rep. 2015 Dec 18; 5:18115.
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Product Notes
The NSC23005 sodium (Catalog #AAA3602713) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "NSC23005 sodium, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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