Structure
Lucigenin, Inhibitor
Lucigenin
Purity
98.00%
Synonyms
Lucigenin; NSC-151912; L-6868; inhibitor
Purity/Purification
98.00%
Form/Format
Solid. Powder
Solubility
DMSO: 25mg/mL (48.97mM)
(<1mg/ml refers to the product slightly soluble or insoluble)
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C28H22N4O6
SMILES
C[N+]1=C2C=CC=CC2=C(C3=C4C=CC=CC4=[N+](C)C5=C3C=CC=C5)C6=C1C=CC=C6.O=N([O-])=O.O=N([O-])=O
CAS Number
2315-97-1
Target & IC50
Others
In Vitro
Upon single-electron reduction of Lucigenin by a radical species the subsequent form of Lucigenin presents amplified chemiluminescence which is measurable and can be correlated to the respective amount of reactive radical species present in the system. In addition to indicating the presence of radicals in cells, Lucigenin shows interaction with redox-active oxidoreductase enzymes. Lucigenin is shown to mediate the reduction of cytochrome C by xanthine oxidase and to increase the rate of NADPH oxidation.
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
-80 degree C for 2 years in solvent
Structure
Structure
Related Product Information for Lucigenin, inhibitor
Lucigenin (L-6868) is a chemiluminescent probe used to indicate the presence of endogenously generated superoxide anion radicals in cells.
References
Li Y, et al. Validation of lucigenin (bis-N-methylacridinium) as a chemilumigenic probe for detecting superoxide anion radical production by enzymatic and cellular systems. J Biol Chem. 1998 Jan 23;273(4):2015-23.
Li Y, et al. Validation of lucigenin (bis-N-methylacridinium) as a chemilumigenic probe for detecting superoxide anion radical production by enzymatic and cellular systems. J Biol Chem. 1998 Jan 23;273(4):2015-23.
Rost M, et al. What do we measure with luminol-, lucigenin- and penicillin-amplified chemiluminescence 1. Investigations with hydrogen peroxide and sodium hypochlorite. J Biolumin Chemiluminutes. 1998 Nov-Dec;13(6):355-63.
Rost M, et al. What do we measure with luminol-, lucigenin- and penicillin-amplified chemiluminescence 1. Investigations with hydrogen peroxide and sodium hypochlorite. J Biolumin Chemiluminutes. 1998 Nov-Dec;13(6):355-63.
Li Y, et al. Validation of lucigenin (bis-N-methylacridinium) as a chemilumigenic probe for detecting superoxide anion radical production by enzymatic and cellular systems. J Biol Chem. 1998 Jan 23;273(4):2015-23.
Rost M, et al. What do we measure with luminol-, lucigenin- and penicillin-amplified chemiluminescence 1. Investigations with hydrogen peroxide and sodium hypochlorite. J Biolumin Chemiluminutes. 1998 Nov-Dec;13(6):355-63.
Rost M, et al. What do we measure with luminol-, lucigenin- and penicillin-amplified chemiluminescence 1. Investigations with hydrogen peroxide and sodium hypochlorite. J Biolumin Chemiluminutes. 1998 Nov-Dec;13(6):355-63.
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Product Notes
The Lucigenin (Catalog #AAA5755860) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Lucigenin, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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