Isoscoparin, Inhibitor
Isoscoparin
Purity
98.00%
Synonyms
Isoscoparin; inhibitor
Purity/Purification
98.00%
Form/Format
Solid. Powder
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C22H22O11
SMILES
COc(cc(cc1)C(Oc2cc(O)c([C@@H]([C@@H]([C@H]3O)O)O[C@H](CO)[C@H]3O)c(O)c22)=CC2=O)c1O
CAS Number
20013-23-4
Target & IC50
Fatty Acid Synthase
NO Synthase
TNF-alpha
NO Synthase
TNF-alpha
In Vitro
Herein, we analysed flavonoids in a yellow grain rice mutant using UHPLC-DAD-ESI-Q-TOF-MS, and identified 19 flavonoids by comparing retention times and accurate mass measurements. Among them, six flavonoids, isoorientin, isoorientin 2"-O-glucoside, vitexin 2"-O-glucoside, isovitexin, Isoscoparin 2"-O-glucoside and Isoscoparin, were isolated and fully identified from the yellow grain rice mutant, and the levels were significantly higher than wild-type, with isoorientin particularly abundant in mutant embryo. Significant differences in total phenolic compounds and antioxidant activity were observed in mutant rice by DPPH, FRAP and TEAC assays[1]
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
-80 degree C for 2 years in solvent
Related Product Information for Isoscoparin, inhibitor
Isoscoparin has antioxidant, and anti-adipogenic effects, it may be a potential therapeutic agent for the prevention and treatment,of obesity. Isoscoparin can significantly inhibit the production of both NO and TNF-alpha+/- at a concentration of 2.0uM.
Product Categories/Family for Isoscoparin, inhibitor
References
Identification and quantification of flavonoids in yellow grain mutant of rice (Oryza sativa L.).Food Chem. 2018 Feb 15;241:154-162.
Identification and quantification of flavonoids in yellow grain mutant of rice (Oryza sativa L.).Food Chem. 2018 Feb 15;241:154-162.
A new phenolic component from Triticum aestivum sprouts and its effects on LPS-stimulated production of nitric oxide and TNF-alpha+/- in RAW 264.7 cells.Phytother Res. 2014 Jul;28(7):1064-70.
Identification and quantification of flavonoids in yellow grain mutant of rice (Oryza sativa L.).Food Chem. 2018 Feb 15;241:154-162.
A new phenolic component from Triticum aestivum sprouts and its effects on LPS-stimulated production of nitric oxide and TNF-alpha+/- in RAW 264.7 cells.Phytother Res. 2014 Jul;28(7):1064-70.
Similar Products
Product Notes
The Isoscoparin (Catalog #AAA5760530) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Isoscoparin, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
