Chemical Structure
ICG-001, inhibitor
ICG-001
Purity
>98%
Synonyms
ICG-001; ICG001; inhibitor
Purity/Purification
>98%
Solubility
DMSO
Formula
C33H32N4O4
SMILES
C1CN ([C@H]2CN (C (=O)[C@@H] (N2C1=O)CC3=CC=C (C=C3)O)CC4=CC=CC5=CC=CC=C54)C (=O)NCC6=CC=CC=C6
CAS Number
780757-88-2
Preparation and Storage
Store at -20 degree C for 3 years (powder form); at -20 degree C for 6 months (Solution base)
Chemical Structure
Chemical Structure
Related Product Information for ICG-001, inhibitor
ICG-001 is a specific inhibitor of Wnt/beta-catenin signaling pathway that inhibits beta-catenin/cyclic AMP response element-binding (CREB) protein transcription (IC50=3 microM).
Product Categories/Family for ICG-001, inhibitor
References
Jasper C.Munro,.et al. Cardiac function and feed efficiency: increased right-heart workload in feed inefficient beef cattle, Livest Sci, 2019, 229 (2019) 159-169
Kim JH,.et al. Small Heterodimer Partner Controls the Virus-Mediated Antiviral Immune Response by Targeting CREB-Binding Protein in the Nucleus, Cell Rep, 2019, May 14;27 (7):2105-2118.e5 PMID: 31091449
Yamaoka R,.et al. CD90 expression in human intrahepatic cholangiocarcinoma is associated with lymph node metastasis and poor prognosis, J Surg Oncol, 2018, Sep;118 (4):664-674 PMID: 30196535Aida Y,.et al. Wnt3a promotes differentiation of human bone marrow-derived mesenchymal stem cells into cementoblast-like cells, In Vitro Cell Dev Biol Anim, 2018, Jun;54 (6):468-476 PMID: 29785536
Kim JH,.et al. Small Heterodimer Partner Controls the Virus-Mediated Antiviral Immune Response by Targeting CREB-Binding Protein in the Nucleus, Cell Rep, 2019, May 14;27 (7):2105-2118.e5 PMID: 31091449
Yamaoka R,.et al. CD90 expression in human intrahepatic cholangiocarcinoma is associated with lymph node metastasis and poor prognosis, J Surg Oncol, 2018, Sep;118 (4):664-674 PMID: 30196535Aida Y,.et al. Wnt3a promotes differentiation of human bone marrow-derived mesenchymal stem cells into cementoblast-like cells, In Vitro Cell Dev Biol Anim, 2018, Jun;54 (6):468-476 PMID: 29785536
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Product Notes
The ICG-001 (Catalog #AAA386627) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "ICG-001, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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