Structure
CCT-031374 hydrobromide, Inhibitor
CCT-031374 hydrobromide
Purity
>98% (HPLC)
Synonyms
CCT-031374 hydrobromide; CCT031374 hydrobromide; inhibitor
Purity/Purification
>98% (HPLC)
Target
Beta-catenin
Receptor
Beta-catenin
Chemical Name
1-([1, 1'-biphenyl]-4-yl)-2-(2, 3-dihydro-9H-benzo[d]imidazo[1, 2-a]imidazol-9-yl)ethan-1-one hydrochloride
SMILES
O=C(C4=CC=C(C5=CC=CC=C5)C=C4)CN1C3=C(C=CC=C3)N2C1=NCC2.Br
Molecular Formula
C23H19N3O.HBr
CAS Number
1219184-91-4
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for CCT-031374 hydrobromide, inhibitor
A novel small-molecule Wnt signaling inhibitor that inhibits TCF-dependent transcription with IC50 of 6.1uM in 7dF3 reporter assay; promotes beta-catenin degradation and lowers beta-catenin levels in mouse L-cells, blockes the growth of a number of cancer cell lines including SW480 colon cancer cells (IC50=13.2uM); blocks free beta-catenin levels in BIO-stimulated HEK293 cells.
Product Categories/Family for CCT-031374 hydrobromide, inhibitor
References
1. Ewan K, et al. Cancer Res. 2010 Jul 15; 70 (14):5963-73.
2. Yang Y, et al. Neuroscience. 2013 Sep 17; 248:383-91.
3. Liu B, et al. Int J Mol Med. 2015 Dec; 36 (6):1572-82.
2. Yang Y, et al. Neuroscience. 2013 Sep 17; 248:383-91.
3. Liu B, et al. Int J Mol Med. 2015 Dec; 36 (6):1572-82.
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Product Notes
The CCT-031374 hydrobromide (Catalog #AAA3600825) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "CCT-031374 hydrobromide, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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