Chemical Structure
Galanin Receptor Ligand M35, Inhibitor | M35, inhibitor
Galanin Receptor Ligand M35 TFA (142846-71-7 free base)
Purity
0.9945
Synonyms
Galanin Receptor Ligand M35; Galanin Receptor Ligand M35 TFA (142846-71-7 free base); Galanin Receptor Ligand M35 TFA; M35; inhibitor
Purity/Purification
0.9945
Form/Format
Solid
Solubility
DMSO: 10mM
(<1mg/ml refers to the product slightly soluble or insoluble)
(<1mg/ml refers to the product slightly soluble or insoluble)
SMILES
C[C@@H](O)[C@H](NC([C@@H](NC(CN)=O)CC1=CNC2=CC=CC=C21)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N3CCC[C@H]3C(N4CCC[C@H]4C(N5CCC[C@H]5C(NCC(N[C@H](C(N[C@H](C(N6CCC[C@H]6C(N[C@H](C(N[C@H](C(N)=O)CCCNC(N)=N)=O)CC7=CC=CC=C7)=O)=O)CO)=O)CC8=CC=CC=C8)=O)=O)=O)=O)=O)=O)CC(C)C)=O)CC(C)C)=O)CC9=CC=C(O)C=C9)=O)=O)C)=O)CO)=O)CC(N)=O)=O)CC(C)C)=O.OC(C(F)(F)F)=O
Formula
C109H154N27F3O28
In vitro
Galanin Receptor Ligand M35 TFA has a dual effect on the galanin mediated inhibition of Forskolin stimulated cyclic AMP production in Rin m 5F cells. Co-applied with galanin (10), Galanin Receptor Ligand M35 TFA at low concentrations (1) is able to reverse the inhibitory effect of galanin. But when present at higher concentrations (15 and 30), Galanin Receptor Ligand M35 TFA acts as a galanin receptor agonist, inhibiting the forskolin stimulated production of cAMP[1].
Preparation and Storage
Store at 0-4 degree C for short term (days to weeks), or -20 degree C for long term (months).
Chemical Structure
Chemical Structure
Related Product Information for M35, inhibitor
Galanin Receptor Ligand M35 TFA is a high-affinity ligand and antagonist of galanin receptor (Kd=0.1).
Product Categories/Family for M35, inhibitor
References
Kask K, et al. Binding and agonist/antagonist actions of M35, galanin(1-13)-bradykinin(2-9)amide chimeric peptide, in Rin m 5F insulinoma cells. Regul Pept. 1995 Nov 10;59(3):341-8.
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Product Notes
The M35 (Catalog #AAA5765439) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Galanin Receptor Ligand M35, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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