Structure
Foxy-5, Inhibitor
Foxy-5
Purity
>98% (HPLC)
Synonyms
Foxy-5; formyl-Met-Asp-Gly-Cys-Glu-Leu; Foxy5; inhibitor
Purity/Purification
>98% (HPLC)
Target
Wnt/beta/catenin
Receptor
Wnt/beta/catenin
Chemical Name
(2S, 5S, 8R, 14S)-5-(2-carboxyethyl)-14-((S)-2-formamido-4-(methylthio)butanamido)-2-isobutyl-8-(mercaptomethyl)-4, 7, 10, 13-tetraoxo-3, 6, 9, 12-tetraazahexadecanedioic acid
SMILES
CC(C)C[C@@H](C(O)=O)NC([C@H](CCC(O)=O)NC([C@H](CS)NC(CNC([C@H](CC(O)=O)NC([C@H](CCSC)NC=O)=O)=O)=O)=O)=O
Molecular Formula
C26H42N6O12S2
CAS Number
881188-51-8
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for Foxy-5, inhibitor
Foxy-5 is a novel Wnt-5A mimicking hexapeptide that inhibits breast cancer metastasis in vivo by targeting cell motility; also significantly inhibits the initial metastatic dissemination of prostate cancer cells to regional and distal lymph nodes, specifically targets invasion without affecting apoptosis or viability of WNT5A-low prostate cancer cells. Breast Cancer Phase 1 Clinical
Product Categories/Family for Foxy-5, inhibitor
References
1. Sfholm A, et al. Clin Cancer Res. 2008 Oct 15; 14 (20):6556-63.
2. Ford CE, et al. Proc Natl Acad Sci U S A. 2009 Mar 10; 106 (10):3919-24.
3. Canesin G, et al. PLoS One. 2017 Sep 8; 12 (9):e0184418.
2. Ford CE, et al. Proc Natl Acad Sci U S A. 2009 Mar 10; 106 (10):3919-24.
3. Canesin G, et al. PLoS One. 2017 Sep 8; 12 (9):e0184418.
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Product Notes
The Foxy-5 (Catalog #AAA3606384) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Foxy-5, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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