eukaryotic translation initiation factor 3, Inhibitor
eukaryotic translation initiation factor 3
Purity
98.00%
Synonyms
eukaryotic translation initiation factor 3; inhibitor
Purity/Purification
98.00%
Form/Format
Solid. Powder
Solubility
DMSO: >=110.1mg/mL
(<1mg/ml refers to the product slightly soluble or insoluble)
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C47H84N14O14S
SMILES
NC(CC(N)=O)C(NC(CC(C)C)C(NC(CCC(N)=O)C(NC(CC(C)C)C(NC(CC(C)C)C(NC(CCSC)C(NC(CC(O)=O)C(NC(CCCNC(N)=N)C(NC(C(C)C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O
In Vitro
In mammals, Eukaryotic translation initiation factor 3 is the largest scaffolding initiation factor, made up of 13 subunits (a-m). It is rough ~750 kDa and it controls the assembly of40S ribosomal subunit on mRNA that has a 5' cap or an IRES (Internal Ribosomal Entry Site). Eukaryotic translation initiation factor 3 uses the eIF4F complex or IRES from viruses to position the mRNA strand near the exit site of the 40S ribosome subunit, thus promoting the assembly of the pre-initiation complex [1].
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
-80 degree C for 2 years in solvent
Related Product Information for eukaryotic translation initiation factor 3, inhibitor
Eukaryotic initiation factors (eIF) are proteins involved in the initiation phase of eukaryotic translation. Eukaryotic translation initiation factor 3 binds to the ribosome subunit-mRNA complex. It has been implicated in preventing the large ribosomal subunit from binding the small subunit before it is ready to commence elongation.
Similar Products
Product Notes
The eukaryotic translation initiation factor 3 (Catalog #AAA5764208) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "eukaryotic translation initiation factor 3, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
