SDS-PAGE
Eukaryotic translation initiation factor 3 subunit G Recombinant Protein | EIF3G recombinant protein
Recombinant Human Eukaryotic translation initiation factor 3 subunit G
Gene Names
EIF3G; EIF3S4; EIF3-P42; eIF3-p44; eIF3-delta
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Eukaryotic translation initiation factor 3 subunit G; Recombinant Human Eukaryotic translation initiation factor 3 subunit G; Eukaryotic translation initiation factor 3; EIF3G recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
2-320; Full Length of Mature Protein
Sequence
PTGDFDSKPSWADQVEEEGEDDKCVTSELLKGIPLATGDTSPEPELLPGAPLPPPKEVINGNIKTVTEYKIDEDGKKFKIVRTFRIETRKASKAVARRKNWKKFGNSEFDPPGPNVATTTVSDDVSMTFITSKEDLNCQEEEDPMNKLKGQKIVSCRICKGDHWTTRCPYKDTLGPMQKELAEQLGLSTGEKEKLPGELEPVQATQNKTGKYVPPSLRDGASRRGESMQPNRRADDNATIRVTNLSEDTRETDLQELFRPFGSISRIYLAKDKTTGQSKGFAFISFHRREDAARAIAGVSGFGYDHLILNVEWAKPSTN
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
SDS-PAGE
SDS-PAGE
Related Product Information for EIF3G recombinant protein
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents prature joining of the 40S and 60S ribosomal subunits prior to initiation. This subunit can bind 18S rRNA.
Product Categories/Family for EIF3G recombinant protein
References
Characterization of cDNAs encoding the p44 and p35 subunits of human translation initiation factor eIF3.Block K.L., Vornlocher H.-P., Hershey J.W.B.J. Biol. Chem. 273:31901-31908(1998)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
51.5 kDa
NCBI Official Full Name
eukaryotic translation initiation factor 3 subunit G
NCBI Official Synonym Full Names
eukaryotic translation initiation factor 3 subunit G
NCBI Official Symbol
EIF3G
NCBI Official Synonym Symbols
EIF3S4; EIF3-P42; eIF3-p44; eIF3-delta
NCBI Protein Information
eukaryotic translation initiation factor 3 subunit G
UniProt Protein Name
Eukaryotic translation initiation factor 3 subunit G
Protein Family
UniProt Gene Name
EIF3G
UniProt Synonym Gene Names
eIF3g; eIF-3 RNA-binding subunit
UniProt Entry Name
EIF3G_HUMAN
Uniprot Description
eIF3-delta: eukaryotic translation initiation factor 3 subunit 4. Binds to the 40S ribosome and promotes the binding of methionyl-tRNAi and mRNA. This subunit binds to the 18S rRNA. eIF-3 is composed of at least 12 different subunits. Contains 1 RNA recognition motif (RRM) domain.
Protein type: Translation; Translation initiation; RNA-binding
Chromosomal Location of Human Ortholog: 19p13.2
Cellular Component: cytoplasm; cytosol; eukaryotic translation initiation factor 3 complex; nucleus; perinuclear region of cytoplasm
Molecular Function: nucleotide binding; protein binding; translation initiation factor activity
Biological Process: cellular protein metabolic process; formation of translation preinitiation complex; gene expression; regulation of translational initiation; translation; translational initiation
Research Articles on EIF3G
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Product Notes
The EIF3G eif3g (Catalog #AAA1143259) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 2-320; Full Length of Mature Protein. The amino acid sequence is listed below: PTGDFDSKPS WADQVEEEGE DDKCVTSELL KGIPLATGDT SPEPELLPGA PLPPPKEVIN GNIKTVTEYK IDEDGKKFKI VRTFRIETRK ASKAVARRKN WKKFGNSEFD PPGPNVATTT VSDDVSMTFI TSKEDLNCQE EEDPMNKLKG QKIVSCRICK GDHWTTRCPY KDTLGPMQKE LAEQLGLSTG EKEKLPGELE PVQATQNKTG KYVPPSLRDG ASRRGESMQP NRRADDNATI RVTNLSEDTR ETDLQELFRP FGSISRIYLA KDKTTGQSKG FAFISFHRRE DAARAIAGVS GFGYDHLILN VEWAKPSTN . It is sometimes possible for the material contained within the vial of "Eukaryotic translation initiation factor 3 subunit G, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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