Ermanin, Inhibitor
Ermanin
Purity
98.00%
Synonyms
Ermanin; inhibitor
Purity/Purification
98.00%
Form/Format
Solid. Powder
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C17H14O6
SMILES
COc(cc1)ccc1C(Oc(cc(cc1O)O)c1C1=O)=C1OC
CAS Number
20869-95-8
Target & IC50
NO Synthase
PGE
NOS
PGE
NOS
In Vitro
Bioassay-guided fractionation and purification of the anti-HIV-1-active MeOH extract from the leaves and twigs of Polyalthia sclerophylla led to the isolation of two new compounds, ENT-kaur-sclerodimer (1) and cyclotucanol 3-palmitate (2), along with the known ENT-kaur-16-en-19-oic acid (3), 15 beta-hydroxy- ENT-kaur-16-en-19-oic acid (4), 15 beta-acetoxy- ENT-kaur-16-en-19-oic acid (5), 15-oxo- ENT-kaur-16-en-19-oic acid (6), 16 alpha,17-dihydroxy- ENT-kauran-19-oic acid (7), 16 alpha-hydroxy- ENT-kauran-19-oic acid (xylopic acid) (8), a pseudodimer (15 alpha-hydroxy- ENT-kaur-16-en-19-oic acid/17-hydroxy- ENT-kaur-15-en-19-oic acid) (9), Ermanin, nicotiflorin, and allantoin[1]
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
-80 degree C for 2 years in solvent
Related Product Information for Ermanin, inhibitor
Ermanin shows anti-inflammatory activity by suppressing the iNOS and COX-2 expression. Ermanin may have anti-HIV-1activity. Ermanin also has a high deterrent activity at 40 ppm against Dione juno larvae.
Product Categories/Family for Ermanin, inhibitor
References
Anti-HIV-1 diterpenoids from leaves and twigs of Polyalthia sclerophylla.Planta Med. 2010 May;76(7):721-5.
Anti-HIV-1 diterpenoids from leaves and twigs of Polyalthia sclerophylla.Planta Med. 2010 May;76(7):721-5.
Ermanin: An insect deterrent flavonoid from Passiflora foetida resin.Phytochemistry, 1991, 30(1):153-5.
Anti-HIV-1 diterpenoids from leaves and twigs of Polyalthia sclerophylla.Planta Med. 2010 May;76(7):721-5.
Ermanin: An insect deterrent flavonoid from Passiflora foetida resin.Phytochemistry, 1991, 30(1):153-5.
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Product Notes
The Ermanin (Catalog #AAA5760353) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Ermanin, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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