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Structure

E 6005; RVT-501, Inhibitor

E 6005; RVT-501

Purity
99.3%
Synonyms
E 6005; RVT-501; inhibitor
Ordering
 
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For Research Use Only!
Purity/Purification
99.3%
Form/Format
POWDER
CAS
947620-48-6
Formula
C26H24N4O5
Pathways
Metabolism
Smiles
CNc1nc2cc(c(cc2c(n1)c1cc(ccc1)NC(=O)c1ccc(cc1)C(=O)OC)OC)OC
Receptor
PDE4
Bioactivity
E6005 is a phosphodiesterase 4 (PDE-4) inhibitor potentially for the treatment of atopic dermatitis.
Solubility Note
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.
Preparation and Storage
For 3 years at -20 degree C (powder)
For 2 years -80 degree C in solvent.

Structure

Product Categories/Family for E 6005; RVT-501, inhibitor
References
1. Nemoto O., et al. Effect of topical phosphodiesterase 4 inhibitor E6005 on Japanese children with atopic dermatitis: Results from a randomized, vehicle-controlled exploratory trial. J Dermatol. 2016 Aug; 43 (8):881-7.

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Product Notes

The E 6005; RVT-501 (Catalog #AAA579901) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "E 6005; RVT-501, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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