Structure
CI-976, Inhibitor
CI-976
Purity
>98% (HPLC)
Synonyms
CI-976; PD 128042; inhibitor
Purity/Purification
>98% (HPLC)
Target
Other Targets
Receptor
Other Targets
Chemical Name
2, 2-dimethyl-N-(2, 4, 6-trimethoxyphenyl)-dodecanamide
SMILES
CCCCCCCCCCC(C)(C)C(=O)NC1=C(C=C(C=C1OC)OC)OC
Molecular Formula
C23H39NO4
CAS Number
114289-47-3
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for CI-976, inhibitor
CI-976 (PD 128042) is a potent, selective, orally bioavailable inhibitor of ACAT-1 (Acetyl-CoA acetyltransferase 1) with IC50 of 73nM; decreases plasma total cholesterol, very low density lipoprotein (VLDL) cholesterol, LDL cholesterol, apolipoprotein B, liver cholesteryl esters, and VLDL and LDL cholesteryl ester content in rabbits. Atherosclerosis Discontinued
Product Categories/Family for CI-976, inhibitor
References
1. Field FJ, et al. Lipids. 1991 Jan; 26 (1):1-8.
2. O'Brien PM, et al. J Med Chem. 1994 Jun 10; 37 (12):1810-22.
3. Krause BR, et al. J Lipid Res. 1993 Feb; 34 (2):279-94.
4. Baba T, et al. Mol Cell Biochem. 2013 Apr; 376 (1-2):151-61.
2. O'Brien PM, et al. J Med Chem. 1994 Jun 10; 37 (12):1810-22.
3. Krause BR, et al. J Lipid Res. 1993 Feb; 34 (2):279-94.
4. Baba T, et al. Mol Cell Biochem. 2013 Apr; 376 (1-2):151-61.
Similar Products
Product Notes
The CI-976 (Catalog #AAA3600507) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "CI-976, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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