Structure
CBP-93872, Inhibitor
CBP-93872
Purity
>98% (HPLC)
Synonyms
CBP-93872; CBP93872; CBP 93872; inhibitor
Purity/Purification
>98% (HPLC)
Target
ATM/ATR
Receptor
ATM/ATR
Chemical Name
1-amino-3-((2-bromo-4-methylphenyl)amino)propan-2-ol
SMILES
OC(CNC1=CC=C(C)C=C1Br)CN
Molecular Formula
C10H15BrN2O
CAS Number
67427-51-4
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for CBP-93872, inhibitor
A potent G2 checkpoint inhibitor that specifically abrogates the DNA double-stranded break (DSB)-induced G2 checkpoint; directly suppresses the growth of p53-mutated cancer cell lines with wild-type CDKN2A by eliciting G (1) arrest, but not CDKN2A-deleted and/or wild-type p53 lines; decreases phospho-cdc2 Y15 by inhibiting phosphorylation of Chk1; specifically inhibits DSB-mediated and Nbs1-dependent activation of ATR.
Product Categories/Family for CBP-93872, inhibitor
References
1. Harada N, et al. Anticancer Drugs. 2011 Nov; 22 (10):986-94.
2. Hirokawa T, et al. Cancer Res. 2014 Jul 15; 74 (14):3880-9.
3. Iwata T, et al. PLoS One. 2017 May 30; 12 (5):e0178221.
2. Hirokawa T, et al. Cancer Res. 2014 Jul 15; 74 (14):3880-9.
3. Iwata T, et al. PLoS One. 2017 May 30; 12 (5):e0178221.
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Product Notes
The CBP-93872 (Catalog #AAA3605569) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "CBP-93872, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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