Betrixaban maleate, Inhibitor
Betrixaban maleate
Purity
>98% (HPLC)
Synonyms
Betrixaban maleate; inhibitor
Purity/Purification
>98% (HPLC)
Suitability
DMSO: 22mg/mL
Target
Factor Xa
Receptor
Factor Xa
SMILES
OC(=O)C=C/C(O)=O.COc1ccc(NC(=O)c2ccc(cc2)C(=N)N(C)C)c(c1)C(=O)Nc1ccc(Cl)cn1
Molecular Formula
C27H26ClN5O7
CAS Number
936539-80-9
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Related Product Information for Betrixaban maleate, inhibitor
Betrixaban is a non-vitamin K oral anticoagulant whose action is driven by the competitive and reversible inhibition of the factor Xa. It was selected among all lead compounds due to its low hERG channel affinity while sustaining its factor Xa inhibition capacity. Betrixaban now developed by Portola Pharmaceuticals Inc. is prescribed as a venous thromboembolism (VTE) prophylactic for adult patients with moderate to severe restricted motility or with other risks for VTE. VTE can be manifested as deep vein thrombosis or pulmonary embolism and it is a leading cause of preventable death in hospitalized patients.
Product Categories/Family for Betrixaban maleate, inhibitor
References
1.Zhang P et al. Discovery of Betrixaban (PRT054021) N-(5-chloropyridin-2-yl)-2-(4-(NN-dimethylcarbamimidoyl)benzamido)-5-methoxybenzamide a highly potent selective and orally efficacious factor Xa inhibitor. Bioorg Med Chem Lett. 2009 Apr 15; 19 (8):21
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Product Notes
The Betrixaban maleate (Catalog #AAA3609827) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Betrixaban maleate, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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