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Atranorin, Inhibitor

Atranorin

Purity
98.00%
Synonyms
Atranorin; inhibitor
Ordering
For Research Use Only!
Purity/Purification
98.00%
Form/Format
Solid. Powder
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C19H18O8
SMILES
Cc1cc(O)c(C=O)c(O)c1C(Oc1c(C)c(O)c(C(OC)=O)c(C)c1)=O
CAS Number
479-20-9
Target & IC50
NO Synthase
In Vitro
Three lichen secondary metabolites Atranorin (1), evernic acid (2), and usnic acid (3), were evaluated for their in vitro clastogenic and antiproliferative effects on human lymphocytes using the cytochalasin-B blocked micronucleus (CBMN) assay at concentrations of 2microg/mL, 4microg/mL and 6microg/mL of final culture solution. Atranorin at concentrations of 2microg/mL and 4microg/mL decreasing the frequency of MN only for 11.1% and 1.8%, while in concentration of 6microg/mL increases the frequency of MN for 9.6 %[1]
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Related Product Information for Atranorin, inhibitor
Atranorin shows significant antinociceptive and antiinflammatory activities, it has a relevant redox-active action, acting as a pro-oxidant or antioxidant agent depending on the radical, also, it will exert cytoprotective effects on cells under oxidative stress induced by H(2)O(2).
Product Categories/Family for Atranorin, inhibitor
References
Clastogenic effect of atranorin, evernic acid, and usnic acid on human lymphocytes.Nat Prod Commun. 2014 Apr;9(4):503-4.
Clastogenic effect of atranorin, evernic acid, and usnic acid on human lymphocytes.Nat Prod Commun. 2014 Apr;9(4):503-4.
Redox properties and cytoprotective actions of atranorin, a lichen secondary metabolite. Toxicol In Vitro. 2011 Mar;25(2):462-8.

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Product Notes

The Atranorin (Catalog #AAA5760156) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Atranorin, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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