6''-O-Malonylgenistin, Inhibitor

6''-O-Malonylgenistin

Cat. Num. AAA5760070

• Purity: 98.00%
• Synonyms: 6''-O-Malonylgenistin; inhibitor

• Purity/Purification: 98.00%
• Form/Format: Solid. Powder

• Solubility: <1mg/ml refers to the product slightly soluble or insoluble
• Formula: C24H22O13
• SMILES: O[C@@H]1[C@@H](COC(=O)CC(O)=O)O[C@@H](Oc2cc(O)c3c(c2)occ(-c2ccc(O)cc2)c3=O)[C@H](O)[C@H]1O
• CAS Number: 51011-05-3
• Target & IC50: Others
• In Vitro: The isoflavone concentration in soybean samples was analyzed on a C 18 reverse-phase column using a two-step gradient solvent system. Producing soybean hydrolysate led to a nearly 40% loss of isoflavones compared with the original soybean flour, but the isoflavone composition did not change and the dominant isoflavone chemicals remained as 6''-O-Malonylgenistin and 6''-O-malonyldaidzin. Ion exchange chromatography affected significantly both the content and the composition of the isoflavones. The dominant isoflavones in the ion-exchanged fraction were aglycones and nonacylated isoflavones, accounting for 95.8% of the total amount of 987.7microg/g. It was calculated that the isoflavone content in the soybean ACE inhibitory peptide fraction was 25 times less than the minimal effective isoflavone dose reported. In vitro study also showed that adding isoflavones into both soybean flour hydrolysate and soybean ACE inhibitory peptide samples to a concentration of as high as 31.5% (w/w) did not affect ACE inhibitory activity (IC 50 values)[1]
• Preparation and Storage: Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent

Structure

Related Product Information for 6''-O-Malonylgenistin, inhibitor

6''-O-Malonylgenistin possesses a hepatoprotective activity.

References

Isoflavone content and its potential contribution to the antihypertensive activity in soybean Angiotensin I converting enzyme inhibitory peptides.J Agric Food Chem. 2008 Nov 12;56(21):9899-904.
Isoflavone content and its potential contribution to the antihypertensive activity in soybean Angiotensin I converting enzyme inhibitory peptides.J Agric Food Chem. 2008 Nov 12;56(21):9899-904.
Isoflavonoid composition of a callus culture of the relict tree Maackia amurensis Rupr. et Maxim.J Agric Food Chem. 2008 Aug 27;56(16):7023-31.