3,8-Di-O-methylellagic acid, Inhibitor
3,8-Di-O-methylellagic acid
Purity
98.00%
Synonyms
3; 8-Di-O-methylellagic acid; inhibitor
Purity/Purification
98.00%
Form/Format
Solid. Powder
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C16H10O8
SMILES
COc(c(O)cc(C(Oc1c2OC)=O)c3-c1c1cc2O)c3OC1=O
CAS Number
2239-88-5
Target & IC50
Antifection
NO Synthase
TNF-alpha
NO Synthase
TNF-alpha
In Vitro
The methanolic extract from the barks of the medicinal plant Qualea parviflora (Vochysiaceae) was fractionated by column chromatography over silica gel followed by gel permeation over Sephadex LH-20 to give 3,3'-di-O-methylellagic acid-4-O-beta-D-glucopyranoside (1), 3-O-methylellagic acid-4'-O-alpha-L-rhamnopyranoside (2), 3,3',4-tri-O-methylellagic acid-4'-O-beta-D-glucopyranoside (3), and 3,3'-di-O-methylellagic acid (3,8-Di-O-methylellagic acid,4), together with triterpenes and saponins. We also performed comparative analyses among this species and Q. grandiflora and Q. multiflora using high-pressure liquid chromatography[1]
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
-80 degree C for 2 years in solvent
Related Product Information for 3,8-Di-O-methylellagic acid, inhibitor
3,3'-Di-O-methylellagic acid reveals moderate antibacterial activity, it also shows strong DPPH radical scavenging activities with SC50 of 123.3ug/mL. It has a lower capacity of stimulating murine peritoneal macrophages to release nitric oxide and tumoural-alpha necrose factor
Product Categories/Family for 3,8-Di-O-methylellagic acid, inhibitor
References
Identification of ellagic acid derivatives in methanolic extracts from Qualea species.Z Naturforsch C. 2008 Nov-Dec;63(11-12):794-800.
Identification of ellagic acid derivatives in methanolic extracts from Qualea species.Z Naturforsch C. 2008 Nov-Dec;63(11-12):794-800.
Active compounds from Lagerstroemia speciosa, insulin-like glucose uptake-stimulatory/inhibitory and adipocyte differentiation-inhibitory activities in 3T3-L1 cells.J Agric Food Chem. 2008 Dec 24;56(24):11668-74.
Chemical Constituents with DPPH Radical Scavenging, Elastase Inhnbition and Tyrosinase Inhibition Activities from Cleyera japonica ThunbKorean Society for Biotechnology and Bioengineering, 2011,4, 272-272.
Identification of ellagic acid derivatives in methanolic extracts from Qualea species.Z Naturforsch C. 2008 Nov-Dec;63(11-12):794-800.
Active compounds from Lagerstroemia speciosa, insulin-like glucose uptake-stimulatory/inhibitory and adipocyte differentiation-inhibitory activities in 3T3-L1 cells.J Agric Food Chem. 2008 Dec 24;56(24):11668-74.
Chemical Constituents with DPPH Radical Scavenging, Elastase Inhnbition and Tyrosinase Inhibition Activities from Cleyera japonica ThunbKorean Society for Biotechnology and Bioengineering, 2011,4, 272-272.
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Product Notes
The 3,8-Di-O-methylellagic acid (Catalog #AAA5759990) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "3,8-Di-O-methylellagic acid, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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