Inhibin A (INHA) Recombinant Protein | INHA recombinant protein

Recombinant Inhibin A (INHA)

Cat. Num. AAA2011255

• Applications: SDS-Page, Western Blot, ELISA, Immunoprecipitation
• Purity: > 95%
• Synonyms: Inhibin A (INHA); Recombinant Inhibin A (INHA); INHA recombinant protein

• Host: E Coli
• Purity/Purification: > 95%
• Form/Format: Supplied as lyophilized form in PBS,pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Sequence: The target protein is fused with N-terminal His-Tag, its sequence is listed below.; MGHHHHHHSGSEF-STPP LPWPWSPAAL RLLQRPPEEP AAHADCHRAA LNISFQELGW DRWIVHPPSF IFYYCHGGCG LSPPQDLPLP VPGVPPTPVQ PLSLVPGAQP CCAALPGTMR PLHVRTTSDG GYSFKYEMVP NLLTQHCACI
• Sequence Length: 360

• Applicable Applications for INHA recombinant protein: SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)
• Organism: Bos taurus; Bovine (Cattle)
• Expression System: Prokaryotic expression
• Residues: Ser227-Ile360 (Accession # P07994) with N-terminal His-Tag
• Endotoxin Level: <1.0EU per 1ug (determined by the LAL method)
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Preparation and Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.; Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.

SDS-Page

NCBI and Uniprot Product Information

• NCBI GI #: 84000571
• NCBI GeneID: 281254
• NCBI Accession #: NP_776519.2
• NCBI GenBank Nucleotide #: NM_174094.4
• UniProt Accession #: P07994; Q2TBQ2
• Molecular Weight: 16.1kDa
• NCBI Official Full Name: inhibin alpha chain
• NCBI Official Synonym Full Names: inhibin, alpha<
• NCBI Official Symbol: INHA
• NCBI Protein Information: inhibin alpha chain; inhibin A
• UniProt Protein Name: Inhibin alpha chain
• Protein Family: Inhibin
• UniProt Gene Name: INHA
• UniProt Entry Name: INHA_BOVIN

Uniprot Description

Function: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.

Subunit structure: Dimeric, linked by one or more disulfide bonds. Inhibin A is a dimer of alpha and beta-A. Inhibin B is a dimer of alpha and beta-B.

Subcellular location: Secreted.

Post-translational modification: Proteolytic processing yields a number of bioactive forms, consisting either solely of the mature alpha chain, of the most N-terminal propeptide linked through a disulfide bond to the mature alpha chain, or of the entire proprotein.

Sequence similarities: Belongs to the TGF-beta family.