Integrin-linked kinase-associated serine/threonine phosphatase 2C (Ilkap) Recombinant Protein | Ilkap recombinant protein
Recombinant Mouse Integrin-linked kinase-associated serine/threonine phosphatase 2C (Ilkap)
Gene Names
Ilkap; PP2C-DELTA; 0710007A14Rik; 1600009O09Rik
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Integrin-linked kinase-associated serine/threonine phosphatase 2C (Ilkap); Recombinant Mouse Integrin-linked kinase-associated serine/threonine phosphatase 2C (Ilkap); Ilkap recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-392, full length protein
Sequence
MDLFGDLPEPERAPRPSAGKEAQGRPVLFEDLPPASSTDSGSGGPLLFDDLPPAASGNSGSLATSGSQVVKTEGKGAKRKAPEEEKNGGEELVEKKVCKASSVIFGLKGYVAERKGEREEMQDAHVILNDITQECNPPSSLITRVSYFAVFDGHGGIRASKFAAQNLHQNLIRKFPKGDIISVEKTVKRCLLDTFKHTDEEFLKQASSQKPAWKDGSTATCVLAVDNILYIANLGDSRAILCRYNEESQKHAALSLSKEHNPTQYEERMRIQKAGGNVRDGRVLGVLEVSRSIGDGQYKRCGVTSVPDIRRCQLTPNDRFILLACDGLFKVFTPEEAVNFILSCLEDDKIQTREGKPAVDARYEAACNRLANKAVQRGSADNVTVMVVRIGH
Sequence Length
392
Species
Mouse
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for Ilkap recombinant protein
This protein is a protein serine
threonine phosphatase of the PP2C family. This protein can interact with integrin-linked kinase (ILK
ILK1), a regulator of integrin mediated signaling, and regulate the kinase activity of ILK. Through the interaction with ILK, this protein may selectively affect the signaling process of ILK-mediated glycogen synthase kinase 3 beta (GSK3beta), and thus participate in Wnt signaling pathway.
threonine phosphatase of the PP2C family. This protein can interact with integrin-linked kinase (ILK
ILK1), a regulator of integrin mediated signaling, and regulate the kinase activity of ILK. Through the interaction with ILK, this protein may selectively affect the signaling process of ILK-mediated glycogen synthase kinase 3 beta (GSK3beta), and thus participate in Wnt signaling pathway.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
30,043 Da
NCBI Official Full Name
integrin-linked kinase-associated serine/threonine phosphatase 2C isoform 1
NCBI Official Synonym Full Names
integrin-linked kinase-associated serine/threonine phosphatase 2C
NCBI Official Symbol
Ilkap
NCBI Official Synonym Symbols
PP2C-DELTA; 0710007A14Rik; 1600009O09Rik
NCBI Protein Information
integrin-linked kinase-associated serine/threonine phosphatase 2C
UniProt Protein Name
Integrin-linked kinase-associated serine/threonine phosphatase 2C
UniProt Gene Name
Ilkap
UniProt Synonym Gene Names
ILKAP
Uniprot Description
Protein phosphatase that may play a role in regulation of cell cycle progression via dephosphorylation of its substrates whose appropriate phosphorylation states might be crucial for cell proliferation. Selectively associates with integrin linked kinase (ILK), to modulate cell adhesion and growth factor signaling. Inhibits the ILK-GSK3B signaling axis and may play an important role in inhibiting oncogenic transformation ().
Research Articles on Ilkap
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Product Notes
The Ilkap ilkap (Catalog #AAA1349506) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-392, full length protein. The amino acid sequence is listed below: MDLFGDLPEP ERAPRPSAGK EAQGRPVLFE DLPPASSTDS GSGGPLLFDD LPPAASGNSG SLATSGSQVV KTEGKGAKRK APEEEKNGGE ELVEKKVCKA SSVIFGLKGY VAERKGEREE MQDAHVILND ITQECNPPSS LITRVSYFAV FDGHGGIRAS KFAAQNLHQN LIRKFPKGDI ISVEKTVKRC LLDTFKHTDE EFLKQASSQK PAWKDGSTAT CVLAVDNILY IANLGDSRAI LCRYNEESQK HAALSLSKEH NPTQYEERMR IQKAGGNVRD GRVLGVLEVS RSIGDGQYKR CGVTSVPDIR RCQLTPNDRF ILLACDGLFK VFTPEEAVNF ILSCLEDDKI QTREGKPAVD ARYEAACNRL ANKAVQRGSA DNVTVMVVRI GH. It is sometimes possible for the material contained within the vial of "Integrin-linked kinase-associated serine/threonine phosphatase 2C (Ilkap), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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