IL-1 beta/IL1B Recombinant Protein | IL1B recombinant protein
Recombinant Rat IL-1 beta/IL1B Protein (mature form)
Gene Names
Il1b; IL-1F2
Purity
>98% as determined by SDS-PAGE.
Synonyms
IL-1 beta/IL1B; Recombinant Rat IL-1 beta/IL1B Protein (mature form); IL1B; IL1B recombinant protein
Host
E Coli
Purity/Purification
>98% as determined by SDS-PAGE.
Form/Format
Lyophilized from sterile 40mM Tris, 0.15 M NaCl, pH 7.8
Sequence Positions
Val 117-Ser 268
Sequence Length
268
Species
Rat
Fusion Tag
Mature Form
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -70 degree C. Store it under sterile conditions at -20 degree C to -80 degree C.
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Related Product Information for IL1B recombinant protein
Interleukin-1 beta (IL1 beta or IL1B) also known as catabolin, is a member of the interleukin 1 cytokine family. IL1 is a pleiotropic cytokine. It is involved in the inflammatory response, cell growth, and tissue repair in the cortex. The IL1 superfamily consists of three members, IL1A (IL1 alpha), IL1B (IL1 beta), and IL1 receptor antagonist (IL1Ra). In clinical, it has been reported that Interleukin (IL)-1 may influence Th1/Th2 immune responsiveness and has been implicated in the establishment of successful pregnancy. Proinflammatory interleukin (IL)-1 gene polymorphisms associated with high levels of IL-1beta activity increase the risk for hypochlorhydria and distal gastric carcinoma. IL1B polymorphisms may be involved in susceptibility to SSc. Moreover, the IL2-384-G allele may be a marker for the limited phenotype of systemic sclerosis (SSc).Immune Checkpoint, Immunotherapy, Cancer Immunotherapy, Targeted Therapy
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
Molecular Mass: 17.4 kDa
Actual Protein Molecular Mass: 35 KDa
Actual Protein Molecular Mass: 35 KDa
NCBI Official Full Name
Interleukin-1 beta
NCBI Official Synonym Full Names
interleukin 1 beta
NCBI Official Symbol
Il1b
NCBI Official Synonym Symbols
IL-1F2
NCBI Protein Information
interleukin-1 beta
UniProt Protein Name
Interleukin-1 beta
Protein Family
UniProt Gene Name
Il1b
UniProt Synonym Gene Names
IL-1 beta
NCBI Description
an inflammatory cytokine [RGD, Feb 2006]
Uniprot Description
Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells.
Research Articles on IL1B
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Product Notes
The IL1B il1b (Catalog #AAA2553663) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is Val 117-Ser 268. It is sometimes possible for the material contained within the vial of "IL-1 beta/IL1B, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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