Human Immunoglobulin superfamily member 1 ELISA Kit | IGSF1 elisa kit

Human Immunoglobulin superfamily member 1 ELISA Kit

Cat. Num. AAA288146

• Gene Names: IGSF1; CHTE; p120; IGCD1; IGDC1; INHBP; PGSF2
• Reactivity: Human
• Synonyms: Immunoglobulin superfamily member 1; Human Immunoglobulin superfamily member 1 ELISA Kit; IGSF1 elisa kit

• Reactivity: Human
• Specificity: This assay recognizes recombinant and natural human IgSF1. No significant cross-reactivity or interference was observed.
• Sequence Length: 1317

• Assay Type: Sandwich
• Detection Range: 0.156-10 ng/ml
• Sensitivity: 0.085 ng/mL
• Intra-Assay CV: <=5.1%
• Inter-Assay CV: <=8.6%
• Recovery: 89%
• Preparation and Storage: For long term storage, please store the entire kit at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for IGSF1 elisa kit

Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an antibody specific to IgSF1. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated polyclonal antibody preparation specific for IgSF1 and Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then a TMB substrate solution is added to each well. Only those wells that contain IgSF1, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The concentration of IgSF1 in the samples is then determined by comparing the O.D. of the samples to the standard curve.

NCBI and Uniprot Product Information

• NCBI GI #: 283436131
• NCBI GeneID: 3547
• NCBI Accession #: NP_001164432.1
• NCBI GenBank Nucleotide #: NM_001170961.1
• UniProt Accession #: Q8N6C5; O15070; Q9NTC8; B5MEG2; H9KV64
• Molecular Weight: 149,425 Da
• NCBI Official Full Name: immunoglobulin superfamily member 1 isoform 3
• NCBI Official Synonym Full Names: immunoglobulin superfamily member 1
• NCBI Official Symbol: IGSF1
• NCBI Official Synonym Symbols: CHTE; p120; IGCD1; IGDC1; INHBP; PGSF2
• NCBI Protein Information: immunoglobulin superfamily member 1
• UniProt Protein Name: Immunoglobulin superfamily member 1
• Protein Family: Immunoglobulin superfamily
• UniProt Gene Name: IGSF1
• UniProt Synonym Gene Names: IGDC1; KIAA0364; PGSF2; IgSF1; InhBP
• UniProt Entry Name: IGSF1_HUMAN

NCBI Description

This gene encodes a member of the immunoglobulin-like domain-containing superfamily. Proteins in this superfamily contain varying numbers of immunoglobulin-like domains and are thought to participate in the regulation of interactions between cells. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2010]

Uniprot Description

IGSF1: Seems to be a coreceptor in inhibin signaling, but seems not to be a high-affinity inhibin receptor. Antagonizes activin A signaling in the presence or absence of inhibin B. Necessary to mediate a specific antagonistic effect of inhibin B on activin-stimulated transcription. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Immunoglobulin superfamily; Membrane protein, multi-pass; Membrane protein, integral; Motility/polarity/chemotaxis; Receptor, misc.

Chromosomal Location of Human Ortholog: Xq25

Cellular Component: extracellular region; integral to membrane; membrane

Molecular Function: coreceptor activity; protein binding; receptor activity

Biological Process: regulation of transcription, DNA-dependent; signal transduction

Disease: Hypothyroidism, Central, And Testicular Enlargement