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IGFLR1:Fc Recombinant Protein

IGFLR1:Fc, Recombinant, Human (IGF-like Family Receptor 1, Transmembrane Protein 149, TMEM149, U2 Small Nuclear RNA Auxiliary Factor 1-like 4)

Purity
Highly Purified
>95% (SDS-PAGE)
Synonyms
IGFLR1:Fc; Recombinant; Human (IGF-like Family Receptor 1; Transmembrane Protein 149; TMEM149; U2 Small Nuclear RNA Auxiliary Factor 1-like 4); IGFLR1:Fc recombinant protein
Ordering
For Research Use Only!
Host
Human, HEK 293 cells
Specificity
Binds to its ligand IGFL3 (human) (Prod. No. AG-40B-0090) in the subnanomolar range (< 1ng /ml).
Purity/Purification
Highly Purified
>95% (SDS-PAGE)
Form/Format
Supplied as a lyophilized powder from a 0.2um filtered solution in PBS pH 7.2.
Sequence
Human IGFLR1 (aa 23-154) is fused at the C-terminus to the Fc portion of human IgG1.
Preparation and Storage
Short-term Storage: +4 degree C
Long-term Storage: -20 degree C
Stable for at least 6 months after receipt when stored at -20 degree C.
Related Product Information for IGFLR1:Fc recombinant protein
Insulin-growth factor-like gene family is a new family of proteins consisting of four proteins in humans (IGFL1 to 4) and one in mice (mIGFL). mIGFL is expressed in normal skin in mice and further upregulated during inflammation responses in skin or after skin wounding. In human only IGFL1 expression is increased in psoriatic skin samples. mIGFL and human IGFL1 and 3 interact with specificity and high affinity to a novel receptor named IGF-like family receptor 1 (formerly TMEM-149). Analysis of the amino acid sequence of IGFLR1 indicated that this receptor is likely a novel member of the TNF-R family. IGFLR1 is expressed most abundantly on mouse T cells, suggesting that mIGFL and IGFL1 produced in the skin may potentially exert regulatory functions on T cell responses.
Product Categories/Family for IGFLR1:Fc recombinant protein

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Product Notes

The IGFLR1:Fc (Catalog #AAA636394) is a Recombinant Protein produced from Human, HEK 293 cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Human IGFLR1 (aa 23-154) is fused at the C-terminus to the Fc portion of human IgG1. It is sometimes possible for the material contained within the vial of "IGFLR1:Fc, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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