Testing Data
(044898 binds to its receptor IGFLR1 (human):Fc (human). Method: IGFLR1 (human):Fc was coated on an ELISA plate at 1ug/ml overnight at room temperature. IGFL-3 (human) or a negative control, Omentin (human) , were added (starting at 8ug/ml with a two-fold serial dilution) during one hour and then detected using an anti-DYKDDDDK antibody (HRP).)
IGFL3 recombinant protein
IGFL3, Recombinant, Human (Insulin Growth Factor-like Family Member 3)
Gene Names
IGFL3; UNQ483
Purity
Highly Purified>95% (SDS-PAGE)
Synonyms
IGFL3; Recombinant; Human (Insulin Growth Factor-like Family Member 3); IGFL3 recombinant protein
Host
Human, HEK 293 cells
Specificity
Binds to human IGFLR1 (Prod. No. AG-40B-0087).
Purity/Purification
Highly Purified
>95% (SDS-PAGE)
>95% (SDS-PAGE)
Form/Format
Supplied as a lyophilized powder from a 0.2um filtered solution in PBS pH 7.2.
Sequence
Human IGFL3 (aa 25-125) is fused at the N-terminus to a DYKDDDDK-tag.
Preparation and Storage
Short-term Storage: +4 degree C
Long-term Storage: -20 degree C
Stable for at least 6 months after receipt when stored at -20 degree C.
Long-term Storage: -20 degree C
Stable for at least 6 months after receipt when stored at -20 degree C.
Testing Data
(044898 binds to its receptor IGFLR1 (human):Fc (human). Method: IGFLR1 (human):Fc was coated on an ELISA plate at 1ug/ml overnight at room temperature. IGFL-3 (human) or a negative control, Omentin (human) , were added (starting at 8ug/ml with a two-fold serial dilution) during one hour and then detected using an anti-DYKDDDDK antibody (HRP).)
Testing Data
(044898 binds to its receptor IGFLR1 (human):Fc (human). Method: IGFLR1 (human):Fc was coated on an ELISA plate at 1ug/ml overnight at room temperature. IGFL-3 (human) or a negative control, Omentin (human) , were added (starting at 8ug/ml with a two-fold serial dilution) during one hour and then detected using an anti-DYKDDDDK antibody (HRP).)
Related Product Information for IGFL3 recombinant protein
Insulin-growth factor-like gene family is a new family of proteins consisting of four proteins in humans (IGFL1 to 4) and one in mice (mIGFL). mIGFL is expressed in normal skin in mice and further upregulated during inflammation responses in skin or after skin wounding. In human only IGFL1 expression is increased in psoriatic skin samples. mIGFL and human IGFL1 and 3 interact with specificity and high affinity to a novel receptor named IGF-like family receptor 1 (formerly TMEM-149). Analysis of the amino acid sequence of IGFLR1 indicated that this receptor is likely a novel member of the TNF-R family. IGFLR1 is expressed most abundantly on mouse T cells, suggesting that mIGFL and IGFL1 produced in the skin may potentially exert regulatory functions on T cell responses.
Product Categories/Family for IGFL3 recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
~12kD (SDS-PAGE)
NCBI Official Full Name
insulin growth factor-like family member 3
NCBI Official Synonym Full Names
IGF-like family member 3
NCBI Official Symbol
IGFL3
NCBI Official Synonym Symbols
UNQ483
NCBI Protein Information
insulin growth factor-like family member 3; RPRC483
UniProt Protein Name
Insulin growth factor-like family member 3
Protein Family
UniProt Gene Name
IGFL3
UniProt Entry Name
IGFL3_HUMAN
NCBI Description
IGFL3 belongs to the insulin-like growth factor (IGF; see MIM 147440) family of signaling molecules that play critical roles in cellular energy metabolism and in growth and development, especially prenatal growth (Emtage et al., 2006 [PubMed 16890402]).[supplied by OMIM, Mar 2008]
Uniprot Description
IGFL3: Potential ligand of the IGFLR1 cell membrane receptor. Belongs to the IGFL family.
Protein type: Cytokine; Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 19q13.32
Cellular Component: extracellular region
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Product Notes
The IGFL3 igfl3 (Catalog #AAA637929) is a Recombinant Protein produced from Human, HEK 293 cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Human IGFL3 (aa 25-125) is fused at the N-terminus to a DYKDDDDK-t ag. It is sometimes possible for the material contained within the vial of "IGFL3, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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