Interferon Alpha Recombinant Protein | IFNa recombinant protein

Recombinant Interferon Alpha (IFNa)

Cat. Num. AAA2033407

• Applications: SDS-Page, Western Blot, ELISA, Immunoprecipitation
• Purity: > 90%
• Synonyms: Interferon Alpha; Recombinant Interferon Alpha (IFNa); IFNA1; IFL; LeIF D; IFN; IFN-Alpha; IFNA13; IFN-A; IFNAP22; IFN-Alpha 1b; Interferon Alpha 1b; Interferon; Leukocytic; Leukocyte; Interferon alpha-D; IFNa recombinant protein

• Host: E Coli
• Purity/Purification: > 90%
• Form/Format: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Sequence: CHLPHSH SLAKRRVLTL LRQLRRVSPSSCLQDRNDFA FPQEALGGSQ LQKAQAISVL HEVTQHTFQL FSTEGSAAVWDESLLDRLRT ALDQQLTDLQ ACLRQEEGLP GAP
• Sequence Length: 195

• Applicable Applications for IFNa recombinant protein: SDS-PAGE, Western (WB), ELISA (EIA), Immunoprecipitation (IP).
• Predicted Molecular Mass: 16.0kDa
• Usage: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Endotoxin Level: <1.0EU per 1 ug (determined by the LAL method)
• Expression System: Prokaryotic expression
• Fragment: Cys24~Pro133
• Organism Species: Bovine
• Tag: two N-terminal Tags, His-tag and T7-tag
• Preparation and Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.; Stability Test: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.

SDS-Page

NCBI and Uniprot Product Information

• NCBI GI #: 386800
• NCBI GeneID: 3467
• Molecular Weight: 22,319 Da
• NCBI Official Full Name: interferon-alpha
• NCBI Official Synonym Full Names: interferon, omega 1
• NCBI Official Symbol: IFNW1
• NCBI Protein Information: interferon omega-1
• UniProt Protein Name: Interferon omega-1
• Protein Family: Interferon
• UniProt Gene Name: IFNW1
• UniProt Entry Name: IFNW1_HUMAN

NCBI Description

The protein encoded by this gene is an interferon and possesses antiviral activity. The encoded protein binds to the interferon alpha/beta receptor but not to the interferon gamma receptor. This intronless gene has several pseudogenes spread throughout the genome. [provided by RefSeq, Nov 2015]

Uniprot Description

IFNW1: Belongs to the alpha/beta interferon family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 9p22

Cellular Component: extracellular space

Molecular Function: cytokine activity; hematopoietin/interferon-class (D200-domain) cytokine receptor binding; interferon-alpha/beta receptor binding

Biological Process: adaptive immune response; B cell differentiation; B cell proliferation; cell cycle arrest; cytokine and chemokine mediated signaling pathway; defense response to virus; humoral immune response; natural killer cell activation during immune response; positive regulation of peptidyl-serine phosphorylation of STAT protein; response to exogenous dsRNA; response to virus; T cell activation during immune response