SDS-Page
(Fig.SDS-PAGE analysis of Rat IFN-gamma protein)
IFN-gamma recombinant protein
Rat IFN-gamma protein
Gene Names
Ifng; IFNG2
Purity
>=95% as determined by SDS-PAGE
Synonyms
IFN-gamma; Rat IFN-gamma protein; IFN-gamma recombinant protein
Host
E Coli
Purity/Purification
>=95% as determined by SDS-PAGE
Form/Format
Lyophilized from sterile 20mM Tris, 150mM NaCl pH7.0.
Sequence
Glu23-Cys156
Protein Construction
Amino acid sequence derived from Rat IFNgamma isoform (P01581)(Glu23-Cys156) was expressed.
Protein Length
The recombinant Rat IFN-gamma consists of 134 amino acids and has a predicted molecular mass of 14.8kDa. The apparent molecular mass of the Rat IFN-gamma protein is approximately 14.8kDa in SDS-PAGE under reducing conditions.
Usage Notes
Always centrifuge tubes before opening. It is recommended to centrifuge at 12000 rpm for 1 minute.Then reconstitute the lyophilized Rat IFN-gamma protein using the buffer we provided not less than 100ug/ml, which can then be further diluted to other aqueous solutions.
Preparation and Storage
Lyophilized Rat IFN-gamma protein product should be stored desiccated below -18 degree C for est. 12 months. Upon reconstitution, the protein should be stored at 4 degree C between 2-7 days and below -18 degree C for est. 3 months. For long term storage it is recommended to add a carrier protein (example 0.1% HSA or BSA),aliquot and store below -18 degree C. Please prevent freeze-thaw cycles.
SDS-Page
(Fig.SDS-PAGE analysis of Rat IFN-gamma protein)
SDS-Page
(Fig.SDS-PAGE analysis of Rat IFN-gamma protein)
Related Product Information for IFN-gamma recombinant protein
Description: Recombinant Rat IFN-gamma protein expressed in E Coli.
Background: IFN gamma, also known as IFNG, is a secreted protein which belongs to the type I I interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte effector T cells once antigen-specific immunity develops. IFN gamma has antiviral, immunoregulatory, and anti-tumor properties. IFNG, in addition to having antiviral activity, has important immunoregulatory functions, it is a potent activator of macrophages, and has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. The IFNG monomer consists of a core of six alpha-helices and an extended unfolded sequence in the C-terminal region. IFN gamma is critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. Aberrant IFN gamma expression is associated with a number of autoinflammatory and autoimmune diseases. The importance of IFN gamma in the immune system stems in part from its ability to inhibit viral replication directly, and most importantly from its immunostimulatory and immunomodulatory effects. IFNG also promotes NK cell activity.
Background: IFN gamma, also known as IFNG, is a secreted protein which belongs to the type I I interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte effector T cells once antigen-specific immunity develops. IFN gamma has antiviral, immunoregulatory, and anti-tumor properties. IFNG, in addition to having antiviral activity, has important immunoregulatory functions, it is a potent activator of macrophages, and has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. The IFNG monomer consists of a core of six alpha-helices and an extended unfolded sequence in the C-terminal region. IFN gamma is critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. Aberrant IFN gamma expression is associated with a number of autoinflammatory and autoimmune diseases. The importance of IFN gamma in the immune system stems in part from its ability to inhibit viral replication directly, and most importantly from its immunostimulatory and immunomodulatory effects. IFNG also promotes NK cell activity.
Product Categories/Family for IFN-gamma recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
17,918 Da
NCBI Official Full Name
interferon gamma
NCBI Official Synonym Full Names
interferon gamma
NCBI Official Symbol
Ifng
NCBI Official Synonym Symbols
IFNG2
NCBI Protein Information
interferon gamma; IFN-gamma
UniProt Protein Name
Interferon gamma
UniProt Gene Name
Ifng
UniProt Synonym Gene Names
IFN-gamma
UniProt Entry Name
IFNG_RAT
NCBI Description
an immune molecule produced by T lymphocytes in response to mitogens or antigens [RGD, Feb 2006]
Uniprot Description
Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
Research Articles on IFN-gamma
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Product Notes
The IFN-gamma ifng (Catalog #AAA9719019) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Glu23-Cys1 56. It is sometimes possible for the material contained within the vial of "IFN-gamma, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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