ICAM-2 recombinant protein

Recombinant Human ICAM-2 Protein

Cat. Num. AAA9141827

• Gene Names: ICAM2; CD102
• Purity: >97% by SDS-PAGE.
• Synonyms: ICAM-2; Recombinant Human ICAM-2 Protein; CD102; ICAM-2 recombinant protein

• Host: HEK293 Cells
• Purity/Purification: >97% by SDS-PAGE.
• Form/Format: Lyophilized from a 0.22 um filtered solution of PBS, pH 7.4.
• Sequence: KVFEVHVRPKKLAVEPKGSLEVNCSTTCNQPEVGGLETSLDKILLDEQAQWKHYLVSNISHDTVLQCHFTCSGKQESMNSNVSVYQPPRQVILTLQPTLVAVGKSFTIECRVPTVEPLDSLTLFLFRGNETLHYETFGKAAPAPQEATATFNSTADREDGHRNFSCLAVLDLMSRGGNIFHKHSAPKMLEIY
• Sequence Length: 275

• Species: Human
• Endotoxin: Please contact us for more information.
• Reconstitution: Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water.
• Tag: Fc, 6xHis tag at the C-terminus
• Preparation and Storage: Store the lyophilized protein at -20 degree C to -80 degree C for long term.; After reconstitution, the protein solution is stable at -20 degree C for 3 months, at 2-8 degree C for up to 1 week.

SDS-Page

(Recombinant Human ICAM-2 Protein was determined by SDS-PAGE with Coomassie Blue, showing a band at 60-70 kDa.)

Related Product Information for ICAM-2 recombinant protein

Recombinant Human ICAM-2 Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Lys25-Gln216) of human ICAM-2 (Accession #NP_000864.2) fused with an Fc, 6xHis tag at the C-terminus.

Product Categories/Family for ICAM-2 recombinant protein

CD Antigen

NCBI and Uniprot Product Information

• NCBI GI #: 153082696
• NCBI GeneID: 3384
• NCBI Accession #: NP_000864.2
• NCBI GenBank Nucleotide #: NP_000864.2
• UniProt Accession #: P13598
• NCBI Official Full Name: intercellular adhesion molecule 2
• NCBI Official Synonym Full Names: intercellular adhesion molecule 2
• NCBI Official Symbol: ICAM2
• NCBI Official Synonym Symbols: CD102
• NCBI Protein Information: intercellular adhesion molecule 2
• UniProt Protein Name: Intercellular adhesion molecule 2
• UniProt Gene Name: ICAM2
• UniProt Synonym Gene Names: ICAM-2
• UniProt Entry Name: ICAM2_HUMAN

NCBI Description

The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

ICAM2: ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen- specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Belongs to the immunoglobulin superfamily. ICAM family.

Protein type: Cell adhesion; Membrane protein, integral

Chromosomal Location of Human Ortholog: 17q23.3

Cellular Component: membrane; integral to plasma membrane; plasma membrane; uropod

Molecular Function: integrin binding

Biological Process: cell-cell adhesion; regulation of immune response; extracellular matrix organization and biogenesis; cell adhesion