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Typical Testing Data/Standard Curve (for reference only)

Human Transmembrane Protease, Serine 6 (TMPRSS6) RTU ELISA Kit | TMPRSS6 rtu elisa kit

Human Transmembrane Protease, Serine 6 (TMPRSS6) ELISA Kit

Gene Names
TMPRSS6; IRIDA
Reactivity
Human
Synonyms
Transmembrane Protease; Serine 6 (TMPRSS6); Human Transmembrane Protease; Serine 6 (TMPRSS6) ELISA Kit; Matriptase-2; TMPRSS6 rtu elisa kit
Ordering
For Research Use Only!
Reactivity
Human
Sequence Length
824
Assay Type
Sandwich
Samples
Tissue Homogenates, Cell Lysates or Other Biological Fluids.
Detection Range
0.781-50ng/mL
Sensitivity
0.35ng/mL
RTU ELISA Kit's Advantage
The Ready-To-Use (RTU) Kits require fewer steps in setup and take less time to run. Detection Solutions are pre-diluted and total incubation time is shorter than many other ELISA Kits.
Preparation and Storage
For unopened kits: All the reagents should be kept at 4 degree C upon receipt.
For opened kits: Once the kit is opened, the remaining reagents still need to be stored according to the above storage conditions. In addition, return the unused wells to the foil pouch containing the desiccant pack and reseal along entire edge of zip-seal.

Typical Testing Data/Standard Curve (for reference only)

Typical Testing Data/Standard Curve (for reference only)
Related Product Information for TMPRSS6 rtu elisa kit
Test Principle: The microtiter plate provided in this kit has been pre-coated with an antibody specific to TMPRSS6. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific to TMPRSS6. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain TMPRSS6, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of TMPRSS6 in the samples is then determined by comparing the O.D. of the samples to the standard curve.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
91,333 Da
NCBI Official Full Name
transmembrane protease serine 6 isoform 1
NCBI Official Synonym Full Names
transmembrane serine protease 6
NCBI Official Symbol
TMPRSS6
NCBI Official Synonym Symbols
IRIDA
NCBI Protein Information
transmembrane protease serine 6
UniProt Protein Name
Transmembrane protease serine 6
UniProt Gene Name
TMPRSS6

NCBI Description

The protein encoded by this gene is a type II transmembrane serine proteinase that is found attached to the cell surface. The encoded protein may be involved in matrix remodeling processes in the liver. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

Uniprot Description

Serine protease which hydrolyzes a range of proteins including type I collagen, fibronectin and fibrinogen. Can also activate urokinase-type plasminogen activator with low efficiency. May play a specialized role in matrix remodeling processes in liver. Through the cleavage of HFE2, a regulator of the expression of the iron absorption-regulating hormone hepicidin/HAMP, plays a role in iron homeostasis.

Research Articles on TMPRSS6

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Product Notes

The Human TMPRSS6 tmprss6 (Catalog #AAA4502961) is a RTU ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA4502961 RTU ELISA Kit recognizes Human TMPRSS6. It is sometimes possible for the material contained within the vial of "Transmembrane Protease, Serine 6 (TMPRSS6), RTU ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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